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Descriptor English: Leukocyte-Adhesion Deficiency Syndrome
Descriptor Spanish: Síndrome de Deficiencia de Adhesión del Leucocito
Descriptor Portuguese: Síndrome da Aderência Leucocítica Deficitária
Descriptor French: Déficit d'adhérence leucocytaire
Entry term(s): Deficiency Syndrome, Leukocyte Adhesion
Deficiency Syndrome, Leukocyte-Adhesion
Leukocyte Adhesion Deficiency Syndrome
Leukocyte-Adhesion Deficiency Syndromes
Tree number(s): C16.320.798.719
C20.673.795.719
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D018370
Scope note: Rare, autosomal recessive disorder caused by deficiency of the beta 2 integrin receptors (RECEPTORS, LEUKOCYTE-ADHESION) comprising the CD11/CD18 family of glycoproteins. The syndrome is characterized by abnormal adhesion-dependent functions, especially defective tissue emigration of neutrophils, leading to recurrent infection.
Allowable Qualifiers: BL blood
CF cerebrospinal fluid
CI chemically induced
CL classification
CN congenital
CO complications
DG diagnostic imaging
DH diet therapy
DI diagnosis
DT drug therapy
EC economics
EH ethnology
EM embryology
EN enzymology
EP epidemiology
ET etiology
GE genetics
HI history
IM immunology
ME metabolism
MI microbiology
MO mortality
NU nursing
PA pathology
PC prevention & control
PP physiopathology
PS parasitology
PX psychology
RH rehabilitation
RT radiotherapy
SU surgery
TH therapy
UR urine
VE veterinary
VI virology
Previous Indexing: Immunologic Deficiency Syndromes (1988-1994)
Receptors, Leukocyte-Adhesion/deficiency (1988-1990)
Public MeSH Note: 95
History Note: 95
Entry Version: LEUKOCYTE ADHESION DEFIC SYNDROME
DeCS ID: 32165
Unique ID: D018370
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1995/01/01
Date of Entry: 1994/01/25
Revision Date: 1996/06/13
Leukocyte-Adhesion Deficiency Syndrome - Preferred
Concept UI M0027596
Scope note Rare, autosomal recessive disorder caused by deficiency of the beta 2 integrin receptors (RECEPTORS, LEUKOCYTE-ADHESION) comprising the CD11/CD18 family of glycoproteins. The syndrome is characterized by abnormal adhesion-dependent functions, especially defective tissue emigration of neutrophils, leading to recurrent infection.
Preferred term Leukocyte-Adhesion Deficiency Syndrome
Entry term(s) Deficiency Syndrome, Leukocyte Adhesion
Deficiency Syndrome, Leukocyte-Adhesion
Leukocyte Adhesion Deficiency Syndrome
Leukocyte-Adhesion Deficiency Syndromes



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