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Descriptor English: Isochromosomes
Descriptor Spanish: Isocromosomas
Descriptor Portuguese: Isocromossomos
Descriptor French: Isochromosomes
Entry term(s): Isochromosome
Tree number(s): A11.284.187.570
C23.550.210.430
G05.360.162.570
G05.365.590.175.430
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D018404
Scope note: Metacentric chromosomes produced during MEIOSIS or MITOSIS when the CENTROMERE splits transversely instead of longitudinally. The chromosomes produced by this abnormal division are one chromosome having the two long arms of the original chromosome, but no short arms, and the other chromosome consisting of the two short arms and no long arms. Each of these isochromosomes constitutes a simultaneous duplication and deletion.
Annotation: note category
Allowable Qualifiers: DE drug effects
ES ethics
GE genetics
IM immunology
PH physiology
RE radiation effects
Previous Indexing: Chromosome Aberrations (1966-1994)
specific chromosome (1966-1994)
Public MeSH Note: 95
History Note: 95
DeCS ID: 32171
Unique ID: D018404
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1995/01/01
Date of Entry: 1994/01/25
Revision Date: 2008/07/08
Isochromosomes - Preferred
Concept UI M0027631
Scope note Metacentric chromosomes produced during MEIOSIS or MITOSIS when the CENTROMERE splits transversely instead of longitudinally. The chromosomes produced by this abnormal division are one chromosome having the two long arms of the original chromosome, but no short arms, and the other chromosome consisting of the two short arms and no long arms. Each of these isochromosomes constitutes a simultaneous duplication and deletion.
Preferred term Isochromosomes
Entry term(s) Isochromosome



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