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Descriptor English: Genes, erbB-1
Descriptor Spanish: Genes erbB-1
Descriptor genes erbB-1
Entry term(s) genes EGFR
genes c-erbB-1
genes del receptor del factor de crecimiento epidérmico
genes v-erbB
Scope note: El proto-oncogén c-erbB-1 codifica el receptor del factor de crecimiento epidérmico. Su nombre procede del homólogo viral v-erbB aislado del virus de la eritroblastosis aviar (AEV) contenido como un fragmento del gen c-ErbB-1del pollo que carece del dominio amino terminal de unión al ligando. Existe sobreexpresión de los genes erbB-1 en un amplio rango de tumores, habitualmente en los carcinomas epidermoides de distintas localizaciones y, con menos frecuencia, en los adenocarcinomas. El gen c-erbB-1 humano se localiza en las regiones cromosómicas 7p14 y 7p12.
Descriptor Portuguese: Genes erbB-1
Descriptor French: Gènes erbB-1
Entry term(s): EGFR Gene
EGFR Genes
Epidermal Growth Factor Receptor Genes
Gene, erbB1
Genes, EGFR
Genes, erbB1
c erbB 1 Genes
c erbB 1 Proto Oncogenes
c-erbB-1 Gene
c-erbB-1 Genes
c-erbB-1 Proto-Oncogene
c-erbB-1 Proto-Oncogenes
erbB 1 Genes
erbB-1 Gene
erbB-1 Genes
erbB1 Gene
erbB1 Genes
v erbB Genes
v erbB Oncogenes
v-erbB Gene
v-erbB Genes
v-erbB Oncogene
v-erbB Oncogenes
Tree number(s): G05.360.340.024.340.375.500.791.295.300
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D018773
Scope note: The proto-oncogene c-erbB-1 codes for the epidermal growth factor receptor. Its name originates from the viral homolog v-erbB which was isolated from an avian erythroblastosis virus (AEV) where it was contained as a fragment of the chicken c-ErbB-1 gene lacking the amino-terminal ligand-binding domain. Overexpression of erbB-1 genes occurs in a wide range of tumors, commonly squamous carcinomas of various sites and less commonly adenocarcinomas. The human c-erbB-1 gene is located in the chromosomal region 7p14 and 7p12.
Annotation: spell in titles & translations as erbB-1; GENES, ERBB-2 is also available
Allowable Qualifiers: DE drug effects
ES ethics
GE genetics
IM immunology
PH physiology
RE radiation effects
Previous Indexing: Oncogenes (1986-1994)
Proto-Oncogenes (1985-1994)
Public MeSH Note: 1995
History Note: 1995
Related: ErbB Receptors MeSH
Oncogene Proteins v-erbB MeSH
DeCS ID: 32227
Unique ID: D018773
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1995/01/01
Date of Entry: 1994/05/23
Revision Date: 2018/07/02
Genes, erbB-1 - Preferred
Concept UI M0028104
Scope note The proto-oncogene c-erbB-1 codes for the epidermal growth factor receptor. Its name originates from the viral homolog v-erbB which was isolated from an avian erythroblastosis virus (AEV) where it was contained as a fragment of the chicken c-ErbB-1 gene lacking the amino-terminal ligand-binding domain. Overexpression of erbB-1 genes occurs in a wide range of tumors, commonly squamous carcinomas of various sites and less commonly adenocarcinomas. The human c-erbB-1 gene is located in the chromosomal region 7p14 and 7p12.
Preferred term Genes, erbB-1
Entry term(s) Gene, erbB1
Genes, erbB1
erbB 1 Genes
erbB-1 Gene
erbB-1 Genes
erbB1 Gene
erbB1 Genes
v-erbB Genes - Narrower
Concept UI M0028103
Preferred term v-erbB Genes
Entry term(s) v erbB Genes
v erbB Oncogenes
v-erbB Gene
v-erbB Oncogene
v-erbB Oncogenes
c-erbB-1 Genes - Narrower
Concept UI M0028102
Preferred term c-erbB-1 Genes
Entry term(s) EGFR Gene
EGFR Genes
Epidermal Growth Factor Receptor Genes
Genes, EGFR
c erbB 1 Genes
c erbB 1 Proto Oncogenes
c-erbB-1 Gene
c-erbB-1 Proto-Oncogene
c-erbB-1 Proto-Oncogenes



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