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Descriptor English: Genes, erbB-2
Descriptor Spanish: Genes erbB-2
Descriptor genes c-erbB-2
Entry term(s) genes HER-2
genes erbB-2
genes neu
Scope note: El gen erbB-2 es un proto-oncogén que codifica el receptor erbB-2 (RECEPTOR ERBB-2), una proteína con características estructurales similares al receptor del factor de crecimiento epidérmico. Su nombre procede del oncogén viral homólogo (v-erbB) que es una forma truncada del gen erbB del pollo identificado en el virus de la eritroblastosis aviar. En un significativo número de adenocarcinomas existe sobreexpresión y amplificación del gen. El gen c-erbB-2 humano se localiza en 17q21.2.
Descriptor Portuguese: Genes erbB-2
Descriptor French: Gènes erbB-2
Entry term(s): Gene, HER2
Gene, erbb2
Genes, HER-2
Genes, HER2
Genes, erbb2
Genes, neu
HER-2 Gene
HER-2 Genes
HER2 Gene
HER2 Genes
c erbB 2 Genes
c erbB 2 Proto Oncogenes
c-erbB-2 Gene
c-erbB-2 Genes
c-erbB-2 Proto-Oncogene
c-erbB-2 Proto-Oncogenes
erbB 2 Genes
erbB-2 Gene
erbB-2 Genes
erbb2 Gene
erbb2 Genes
neu Gene
neu Genes
Tree number(s): G05.360.340.024.340.375.500.791.295.305
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D018734
Scope note: The erbB-2 gene is a proto-oncogene that codes for the erbB-2 receptor (RECEPTOR, ERBB-2), a protein with structural features similar to the epidermal growth factor receptor. Its name originates from the viral oncogene homolog (v-erbB) which is a truncated form of the chicken erbB gene found in the avian erythroblastosis virus. Overexpression and amplification of the gene is associated with a significant number of adenocarcinomas. The human c-erbB-2 gene is located at 17q21.2.
Annotation: in titles & translations spell as erbB-2; GENES, ERBB-1 is also available
Allowable Qualifiers: DE drug effects
ES ethics
GE genetics
IM immunology
PH physiology
RE radiation effects
Previous Indexing: Oncogenes (1986-1994)
Proto-Oncogenes (1986-1994)
Public MeSH Note: 1995
History Note: 1995
Related: ErbB Receptors MeSH
Oncogene Proteins v-erbB MeSH
Receptor, ErbB-2 MeSH
DeCS ID: 32226
Unique ID: D018734
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1995/01/01
Date of Entry: 1994/05/23
Revision Date: 2018/06/12
Genes, erbB-2 - Preferred
Concept UI M0028066
Scope note The erbB-2 gene is a proto-oncogene that codes for the erbB-2 receptor (RECEPTOR, ERBB-2), a protein with structural features similar to the epidermal growth factor receptor. Its name originates from the viral oncogene homolog (v-erbB) which is a truncated form of the chicken erbB gene found in the avian erythroblastosis virus. Overexpression and amplification of the gene is associated with a significant number of adenocarcinomas. The human c-erbB-2 gene is located at 17q21.2.
Preferred term Genes, erbB-2
Entry term(s) Gene, HER2
Gene, erbb2
Genes, HER-2
Genes, HER2
Genes, erbb2
Genes, neu
HER-2 Gene
HER-2 Genes
HER2 Gene
HER2 Genes
c erbB 2 Genes
c erbB 2 Proto Oncogenes
c-erbB-2 Gene
c-erbB-2 Genes
c-erbB-2 Proto-Oncogene
c-erbB-2 Proto-Oncogenes
erbB 2 Genes
erbB-2 Gene
erbB-2 Genes
erbb2 Gene
erbb2 Genes
neu Gene
neu Genes



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