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Descriptor English: HL-60 Cells
Descriptor Spanish: Células HL-60
Descriptor células HL-60
Scope note: Línea celular promielocítica derivada de un paciente con leucemia promielocítica aguda. Las células HL-60 carecen de marcadores específicos de las células linfoides pero expresan receptores de superficie para los fragmentos Fc y el complemento. Ellas también muestran actividad fagocítica y responden a los estímulos quimiotácticos. (Hay et al., American Type Culture Collection, 7th ed, pp127-8)
Descriptor Portuguese: Células HL-60
Descriptor French: Cellules HL-60
Entry term(s): Cell, HL60
Cells, HL60
HL 60 Cells
HL-60 Cell
HL60 Cell
HL60 Cells
Tree number(s): A11.251.210.190.465
A11.251.860.180.465
A11.627.340.360.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D018922
Scope note: A promyelocytic cell line derived from a patient with ACUTE PROMYELOCYTIC LEUKEMIA. HL-60 cells lack specific markers for LYMPHOID CELLS but express surface receptors for FC FRAGMENTS and COMPLEMENT SYSTEM PROTEINS. They also exhibit phagocytic activity and responsiveness to chemotactic stimuli. (From Hay et al., American Type Culture Collection, 7th ed, pp127-8)
Annotation: almost always NIM with no subheadings; check HUMAN; do not routinely add LEUKEMIA, PROMYELOCYTIC, ACUTE
Allowable Qualifiers: CH chemistry
CL classification
CY cytology
DE drug effects
EN enzymology
IM immunology
ME metabolism
MI microbiology
PA pathology
PH physiology
PS parasitology
RE radiation effects
TR transplantation
UL ultrastructure
VI virology
Previous Indexing: Cell Line (1979-1995)
Tumor Cells, Cultured (1987-1995)
Public MeSH Note: 96
History Note: 96
DeCS ID: 32726
Unique ID: D018922
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1996/01/01
Date of Entry: 1995/06/08
Revision Date: 2005/07/01
HL-60 Cells - Preferred
Concept UI M0028291
Scope note A promyelocytic cell line derived from a patient with ACUTE PROMYELOCYTIC LEUKEMIA. HL-60 cells lack specific markers for LYMPHOID CELLS but express surface receptors for FC FRAGMENTS and COMPLEMENT SYSTEM PROTEINS. They also exhibit phagocytic activity and responsiveness to chemotactic stimuli. (From Hay et al., American Type Culture Collection, 7th ed, pp127-8)
Preferred term HL-60 Cells
Entry term(s) Cell, HL60
Cells, HL60
HL 60 Cells
HL-60 Cell
HL60 Cell
HL60 Cells



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