| Descriptor English: | Cystic Fibrosis Transmembrane Conductance Regulator | ||||||
| Descriptor Spanish: |
Regulador de Conductancia de Transmembrana de Fibrosis Quística
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| Descriptor Portuguese: | Regulador de Condutância Transmembrana em Fibrose Cística | ||||||
| Descriptor French: | Protéine CFTR | ||||||
| Entry term(s): |
CFTR Protein Chloride channels, ATP gated CFTR Chloride channels, ATP-gated CFTR Protein, CFTR |
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| Tree number(s): |
D12.776.157.530.100.304.500 D12.776.157.530.400.175.125 D12.776.157.530.450.074.500.500.500.500 D12.776.543.550.450.175.125 D12.776.543.585.100.304.500 D12.776.543.585.400.175.125 D12.776.543.585.450.074.500.500.500.500 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D019005 | ||||||
| Scope note: | A chloride channel that regulates secretion in many exocrine tissues. Abnormalities in the CFTR gene have been shown to cause cystic fibrosis. (Hum Genet 1994;93(4):364-8) |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | 126880-72-6 | ||||||
| Previous Indexing: |
Membrane Proteins (1989-1995) |
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| Public MeSH Note: | 96; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR was indexed under MEMBRANE PROTEINS 1989-95 |
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| Online Note: | use CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR (NM) to search CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR 1989-95 |
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| History Note: | 96; was CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR (NM) 1989-95 |
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| DeCS ID: | 32784 | ||||||
| Unique ID: | D019005 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1996/01/01 | ||||||
| Date of Entry: | 1995/05/24 | ||||||
| Revision Date: | 2016/07/01 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Cystic Fibrosis Transmembrane Conductance Regulator
- Preferred
| Concept UI |
M0028383 |
| Scope note | A chloride channel that regulates secretion in many exocrine tissues. Abnormalities in the CFTR gene have been shown to cause cystic fibrosis. (Hum Genet 1994;93(4):364-8) |
| Preferred term | Cystic Fibrosis Transmembrane Conductance Regulator |
| Entry term(s) |
CFTR Protein Chloride channels, ATP gated CFTR Chloride channels, ATP-gated CFTR Protein, CFTR |
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