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Descriptor English: Thapsigargin
Descriptor Spanish: Tapsigargina
Descriptor tapsigargina
Scope note: Lactona sesquiterpénica que se encuentra en las raíces de THAPSIA. Inhibe la recaptación del CALCIO mediada por la ATPASA TRANSPORTADORA DE CA(2+) al interior del RETÍCULO SARCOPLÁSMICO.
Descriptor Portuguese: Tapsigargina
Descriptor French: Thapsigargine
Tree number(s): D02.455.426.392.368.284.500.888
D02.455.849.765.674.500.750.888
D04.663.500.750.888
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D019284
Scope note: A sesquiterpene lactone found in roots of THAPSIA. It inhibits SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Enzyme Inhibitors
Registry Number: 67526-95-8
Previous Indexing: Terpenes (1979-1996)
Public MeSH Note: 97; THAPSIGARGIN was indexed under TERPENES 1979-96
Online Note: use THAPSIGARGIN (NM) to search THAPSIGARGIN 1980-96
History Note: 97; was THAPSIGARGIN (NM) 1979-96
DeCS ID: 32986
Unique ID: D019284
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1997/01/01
Date of Entry: 1996/06/10
Revision Date: 2017/06/20
Thapsigargin - Preferred
Concept UI M0028714
Scope note A sesquiterpene lactone found in roots of THAPSIA. It inhibits SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES.
Preferred term Thapsigargin



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