Search
Descriptor English: Lamivudine
Descriptor Spanish: Lamivudine
Descriptor lamivudina
Entry term(s) (+)-cis-lamivudina
(+-)-trans-lamivudina
(2R-cis)-4-amino-1-(2-(hidroximetil)-1,3-oxatiolan-5-il)-2(1H)-pirimidinona
2',3'-dideoxi-3'-tiacitidina
3TC
lamivudina (3TC)
Scope note: Inhibidor de la transcriptasa inversa y análogo de la ZALCITABINA en el que un átomo de azufre sustituye al carbono de la posición 3' en el anillo de pentosa. Se utiliza en el tratamiento del SIDA.
Descriptor Portuguese: Lamivudina
Descriptor French: Lamivudine
Entry term(s): 2',3' Dideoxy 3' thiacytidine
2',3'-Dideoxy-3'-thiacytidine
2(1H)-Pyrimidinone, 4-amino-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-, (2R-cis)-
3TC Lamivudine
BCH 189
BCH-189
BCH189
Epivir
GR-109714X
GR109714X
Lamivudine, (+)-cis-
Lamivudine, (+-)-trans-
Lamivudine, (2S-cis)-Isomer
Tree number(s): D03.383.742.680.245.500.950.500
D13.570.230.329.950.500
D13.570.230.500.925.500
D13.570.685.245.500.950.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D019259
Scope note: A reverse transcriptase inhibitor and ZALCITABINE analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat HIV disease.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Reverse Transcriptase Inhibitors
Anti-HIV Agents
Registry Number: 2T8Q726O95
CAS Type 1 Name: 2(1H)-Pyrimidinone, 4-amino-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-, (2R-cis)-
Previous Indexing: Cytosine/analogs & derivatives (1991-1992)
Zalcitabine/analogs & derivatives (1993-1996)
Public MeSH Note: 97; LAMIVUDINE was indexed under ZALCITABINE/analogs & derivatives 1993-96 and CYTOSINE/analogs & derivatives 1991-92
Online Note: use LAMIVUDINE (NM) to search LAMIVUDINE 1991-96
History Note: 97; was LAMIVUDINE (NM) 1991-96
DeCS ID: 33070
Unique ID: D019259
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1997/01/01
Date of Entry: 1996/06/10
Revision Date: 2021/10/18
Lamivudine - Preferred
Concept UI M0028682
Scope note A reverse transcriptase inhibitor and ZALCITABINE analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat HIV disease.
Preferred term Lamivudine
Entry term(s) 2',3' Dideoxy 3' thiacytidine
2',3'-Dideoxy-3'-thiacytidine
2(1H)-Pyrimidinone, 4-amino-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-, (2R-cis)-
3TC Lamivudine
Epivir - Narrower
Concept UI M0028684
Preferred term Epivir
Lamivudine, (2S-cis)-Isomer - Narrower
Concept UI M0329185
Preferred term Lamivudine, (2S-cis)-Isomer
BCH-189 - Related but not broader or narrower
Concept UI M0028683
Preferred term BCH-189
Entry term(s) BCH 189
BCH189
GR-109714X - Narrower
Concept UI M0372433
Preferred term GR-109714X
Entry term(s) GR109714X
Lamivudine, (+)-cis- - Narrower
Concept UI M000751242
Preferred term Lamivudine, (+)-cis-
Lamivudine, (+-)-trans- - Narrower
Concept UI M000751245
Preferred term Lamivudine, (+-)-trans-



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey