| Descriptor English: | Kininogen, High-Molecular-Weight | ||||||
| Descriptor Spanish: |
Quininógeno de Alto Peso Molecular
| ||||||
| Descriptor Portuguese: | Cininogênio de Alto Peso Molecular | ||||||
| Descriptor French: | Kininogène de haut poids moléculaire | ||||||
| Entry term(s): |
Fitzgerald Factor HMWK High Molecular Weight Kininogen High Molecular Weight Kininogens High-Molecular-Weight Kininogen High-Molecular-Weight Kininogens Kininogen, High Molecular Weight Kininogens, High Molecular Weight Kininogens, High-Molecular-Weight |
||||||
| Tree number(s): |
D12.644.276.812.654.350 D12.776.124.125.635.480 D12.776.467.812.654.350 D12.776.811.420.350 D23.119.630.480 D23.469.050.375.425.350 D23.529.812.654.350 |
||||||
| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D019679 | ||||||
| Scope note: | A plasma protein, molecular weight of 110 kD, that normally exists in plasma in a 1:1 complex with PREKALLIKREIN. HMWK is split by plasma kallikrein to produce BRADYKININ. The complex is a cofactor in the activation of coagulation factor XII. The product of this reaction, XIIa, in turn activates prekallikrein to KALLIKREINS. (From Stedman, 26th ed) |
||||||
| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
||||||
| Previous Indexing: |
Kininogens (1974-1997) |
||||||
| Public MeSH Note: | 98; see KININOGENS 1989-97 |
||||||
| History Note: | 98; use KININOGENS 1989-97 |
||||||
| Entry Version: | KININOGEN HMW |
||||||
| DeCS ID: | 33486 | ||||||
| Unique ID: | D019679 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1998/01/01 | ||||||
| Date of Entry: | 1997/06/20 | ||||||
| Revision Date: | 2006/07/05 |
-
-
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors
|
|
Kininogen, High-Molecular-Weight
- Preferred
| Concept UI |
M0029210 |
| Scope note | A plasma protein, molecular weight of 110 kD, that normally exists in plasma in a 1:1 complex with PREKALLIKREIN. HMWK is split by plasma kallikrein to produce BRADYKININ. The complex is a cofactor in the activation of coagulation factor XII. The product of this reaction, XIIa, in turn activates prekallikrein to KALLIKREINS. (From Stedman, 26th ed) |
| Preferred term | Kininogen, High-Molecular-Weight |
| Entry term(s) |
Fitzgerald Factor HMWK High Molecular Weight Kininogen High Molecular Weight Kininogens High-Molecular-Weight Kininogen High-Molecular-Weight Kininogens Kininogen, High Molecular Weight Kininogens, High Molecular Weight Kininogens, High-Molecular-Weight |
We want your feedback on the new DeCS / MeSH website
We invite you to complete a survey that will take no more than 3 minutes.
Go to survey
