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Descriptor English: Nicorandil
Descriptor Spanish: Nicorandil
Descriptor nicorandil
Entry term(s) 2-nicotinamidoetil nitrato
Scope note: Derivado de la NIACINAMIDA que está estructuralemtne combinado con nitrato orgánico. Es un abridor de los canales de potasio que causa vasodilatación de las arteriolas y de las grandes arterias coronarias. Sus propiedades tipo nitrato producen dilatación venosa por estimulación de la guanilato ciclasa.
Descriptor Portuguese: Nicorandil
Descriptor French: Nicorandil
Entry term(s): 2 Nicotinamidethyl Nitrate
2 Nicotinamidoethyl Nitrate
2-Nicotinamidethyl Nitrate
2-Nicotinamidoethyl Nitrate
Adancor
Dancor
Ikorel
Nitrate, 2-Nicotinamidethyl
Nitrate, 2-Nicotinamidoethyl
SG 75
SG-75
SG75
Tree number(s): D02.583.575
D03.066.515.530.498
D03.383.725.547.530.498
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D020108
Scope note: A derivative of the NIACINAMIDE that is structurally combined with an organic nitrate. It is a potassium-channel opener that causes vasodilatation of arterioles and large coronary arteries. Its nitrate-like properties produce venous vasodilation through stimulation of guanylate cyclase.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Arrhythmia Agents
Antihypertensive Agents
Vasodilator Agents
Vitamin B Complex
Registry Number: 260456HAM0
CAS Type 1 Name: 3-Pyridinecarboxamide, N-(2-(Nitroxy)ethyl)-
Previous Indexing: Niacinamide/analogs & derivatives (1978-1998)
Nitrates (1978-1982)
Public MeSH Note: 99; NICORANDIL was indexed under NIACINAMIDE 1983-98 & NITRATES 1978-82
History Note: 99; use NICORANDIL (NM) 1978-98
DeCS ID: 33810
Unique ID: D020108
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1999/01/01
Date of Entry: 1998/06/10
Revision Date: 2017/05/24
Nicorandil - Preferred
Concept UI M0029846
Scope note A derivative of the NIACINAMIDE that is structurally combined with an organic nitrate. It is a potassium-channel opener that causes vasodilatation of arterioles and large coronary arteries. Its nitrate-like properties produce venous vasodilation through stimulation of guanylate cyclase.
Preferred term Nicorandil
Entry term(s) 2 Nicotinamidethyl Nitrate
2 Nicotinamidoethyl Nitrate
2-Nicotinamidethyl Nitrate
2-Nicotinamidoethyl Nitrate
Nitrate, 2-Nicotinamidethyl
Nitrate, 2-Nicotinamidoethyl
SG-75 - Narrower
Concept UI M0352053
Preferred term SG-75
Entry term(s) SG 75
SG75
Ikorel - Narrower
Concept UI M0463084
Preferred term Ikorel
Adancor - Narrower
Concept UI M0463082
Preferred term Adancor
Dancor - Narrower
Concept UI M0463083
Preferred term Dancor



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