| Descriptor English: | Peptide Nucleic Acids | ||||||
| Descriptor Spanish: |
Ácidos Nucleicos de Péptidos
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| Descriptor Portuguese: | Ácidos Nucleicos Peptídicos | ||||||
| Descriptor French: | Acides nucléiques peptidiques | ||||||
| Entry term(s): |
Acid, Peptide Nucleic Acids, Peptide Nucleic Nucleic Acid, Peptide Nucleic Acids, Peptide Peptide Nucleic Acid |
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| Tree number(s): |
D13.695.578.424.550 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D020135 | ||||||
| Scope note: | DNA analogs containing neutral amide backbone linkages composed of aminoethyl glycine units instead of the usual phosphodiester linkage of deoxyribose groups. Peptide nucleic acids have high biological stability and higher affinity for complementary DNA or RNA sequences than analogous DNA oligomers. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
Nucleic Acids (1981-1998) Peptides (1993-1998) |
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| Public MeSH Note: | 99 |
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| History Note: | 99 |
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| DeCS ID: | 33847 | ||||||
| Unique ID: | D020135 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1999/01/01 | ||||||
| Date of Entry: | 1998/06/10 | ||||||
| Revision Date: | 2020/05/27 |
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Peptide Nucleic Acids
- Preferred
| Concept UI |
M0029874 |
| Scope note | DNA analogs containing neutral amide backbone linkages composed of aminoethyl glycine units instead of the usual phosphodiester linkage of deoxyribose groups. Peptide nucleic acids have high biological stability and higher affinity for complementary DNA or RNA sequences than analogous DNA oligomers. |
| Preferred term | Peptide Nucleic Acids |
| Entry term(s) |
Acid, Peptide Nucleic Acids, Peptide Nucleic Nucleic Acid, Peptide Nucleic Acids, Peptide Peptide Nucleic Acid |
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