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Descriptor English: Inhibitory Concentration 50
Descriptor Spanish: Concentración 50 Inhibidora
Descriptor concentración inhibidora 50
Entry term(s) IC50
Scope note: Concentración necesaria de un compuesto para reducir in vitro en un 50 por ciento el crecimiento poblacional de organismos, incluidas las células eucariotas. Aunque a menudo se expresa para denotar la actividad antibacteriana in vitro, se utiliza también como patrón de citotoxicidad para las células eucariotas en cultivo.
Descriptor Portuguese: Concentração Inibidora 50
Descriptor French: Concentration inhibitrice 50
Entry term(s): Concentration 50, Inhibitory
IC50
Tree number(s): E05.940.350
G07.690.936.563
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D020128
Scope note: The concentration of a compound needed to reduce population growth of organisms, including eukaryotic cells, by 50% in vitro. Though often expressed to denote in vitro antibacterial activity, it is also used as a benchmark for cytotoxicity to eukaryotic cells in culture.
Annotation: do not confuse with LETHAL DOSE 50, determined in animals
Previous Indexing: Cell Survival/drug effects (1971-1998)
Public MeSH Note: 99
History Note: 99
Related: Microbial Sensitivity Tests MeSH
DeCS ID: 33878
Unique ID: D020128
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1999/01/01
Date of Entry: 1998/06/10
Revision Date: 2016/06/28
Inhibitory Concentration 50 - Preferred
Concept UI M0029868
Scope note The concentration of a compound needed to reduce population growth of organisms, including eukaryotic cells, by 50% in vitro. Though often expressed to denote in vitro antibacterial activity, it is also used as a benchmark for cytotoxicity to eukaryotic cells in culture.
Preferred term Inhibitory Concentration 50
Entry term(s) Concentration 50, Inhibitory
IC50



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