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Descriptor English: Alu Elements
Descriptor Spanish: Elementos Alu
Descriptor elementos Alu
Entry term(s) familia alu
secuencia repetitiva similar a alu
secuencias repetitivas alu
Scope note: La familia de secuencia Alu (denominada así por la restricción de la enzima Alu I de división de endonucleasa) es el elemento de repetición entremezclado que ostenta una mayor repetición en los seres humanos (cerca de un millón de copias). Deriva del componente del ARN 75L de la PARTÍCULA DE RECONOCIMIENTO DE SEÑAL, y contiene un promotor de la polimerasa III del ADN. La transposición de este elemento en regiones codificadoras y reguladoras de genes es la responsable de muchas enfermedades hereditarias.
Descriptor Portuguese: Elementos Alu
Descriptor French: Séquences Alu
Entry term(s): Alu Element
Alu Families
Alu Family
Alu Repetitive Sequence
Alu Repetitive Sequences
Alu-Like Repetitive Sequence
Element, Alu
Elements, Alu
Families, Alu
Family, Alu
Repetitive Sequence, Alu
Repetitive Sequences, Alu
Sequence, Alu Repetitive
Sequences, Alu Repetitive
Tree number(s): G02.111.570.080.708.330.800.800.050
G05.360.080.708.330.800.800.050
G05.360.340.024.425.800.800.050
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D020087
Scope note: The Alu sequence family (named for the restriction endonuclease cleavage enzyme Alu I) is the most highly repeated interspersed repeat element in humans (over a million copies). It is derived from the 7SL RNA component of the SIGNAL RECOGNITION PARTICLE and contains an RNA polymerase III promoter. Transposition of this element into coding and regulatory regions of genes is responsible for many heritable diseases.
Allowable Qualifiers: DE drug effects
ES ethics
GE genetics
IM immunology
PH physiology
RE radiation effects
Previous Indexing: Repetitive Sequences, Nucleic Acid (1981-1998)
Public MeSH Note: 99; see REPETITIVE SEQUENCES, NUCLEIC ACID 1988-98; for ALU REPETITIVE SEQUENCE, ALU FAMILY, and ALU-LIKE REPETITIVE SEQUENCE see REPETITIVE SEQUENCES, NUCLEIC ACID 1988-98
History Note: 99; use REPETITIVE SEQUENCES, NUCLEIC ACID 1988-98; for ALU REPETITIVE SEQUENCE, ALU FAMILY, and ALU-LIKE REPETITIVE SEQUENCE use REPETITIVE SEQUENCES, NUCLEIC ACID 1988-98
Related: Mutagenesis, Insertional MeSH
DeCS ID: 33905
Unique ID: D020087
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1999/01/01
Date of Entry: 1998/06/10
Revision Date: 2008/07/08
Alu Elements - Preferred
Concept UI M0029813
Scope note The Alu sequence family (named for the restriction endonuclease cleavage enzyme Alu I) is the most highly repeated interspersed repeat element in humans (over a million copies). It is derived from the 7SL RNA component of the SIGNAL RECOGNITION PARTICLE and contains an RNA polymerase III promoter. Transposition of this element into coding and regulatory regions of genes is responsible for many heritable diseases.
Preferred term Alu Elements
Entry term(s) Alu Element
Alu Families
Alu Family
Alu Repetitive Sequence
Alu Repetitive Sequences
Element, Alu
Elements, Alu
Families, Alu
Family, Alu
Repetitive Sequence, Alu
Repetitive Sequences, Alu
Sequence, Alu Repetitive
Sequences, Alu Repetitive
Alu-Like Repetitive Sequence - Related but not broader or narrower
Concept UI M0029814
Preferred term Alu-Like Repetitive Sequence



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