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Descriptor English: Creatine Kinase
Descriptor Spanish: Creatina Quinasa
Descriptor creatina cinasa
Entry term(s) creatina fosfocinasa
creatina quinasa
Scope note: Transferasa que cataliza la formación de FOSFOCREATINA a partir de ATP + CREATINA. La reacción almacena energía del ATP como fosfocreatina. En los tejidos humanos se han identificado tres ISOENZIMAS citoplasmáticas: el tipo MM del MÚSCULO ESQUELÉTICO, el tipo MB del tejido miocárdico y el tipo BB del tejido nervioso, así como una isoenzima mitocondrial. El término macro-creatina cinasa se refiere al complejo de creatina cinasa con otras proteínas séricas.
Descriptor Portuguese: Creatina Quinase
Descriptor French: Creatine kinase
Entry term(s): ADP Phosphocreatine Phosphotransferase
ATP Creatine Phosphotransferase
Creatine Phosphokinase
Creatine Phosphotransferase, ATP
Kinase, Creatine
Macro Creatine Kinase
Macro-Creatine Kinase
Phosphocreatine Phosphotransferase, ADP
Phosphokinase, Creatine
Phosphotransferase, ADP Phosphocreatine
Phosphotransferase, ATP Creatine
Tree number(s): D08.811.913.696.640.150
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D003402
Scope note: A transferase that catalyzes formation of PHOSPHOCREATINE from ATP + CREATINE. The reaction stores ATP energy as phosphocreatine. Three cytoplasmic ISOENZYMES have been identified in human tissues: the MM type from SKELETAL MUSCLE, the MB type from myocardial tissue and the BB type from nervous tissue as well as a mitochondrial isoenzyme. Macro-creatine kinase refers to creatine kinase complexed with other serum proteins.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.7.3.2
CAS Type 1 Name: ATP:creatine N-phosphotransferase
DeCS ID: 3419
Unique ID: D003402
NLM Classification: QU 141
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2005/06/30
Creatine Kinase - Preferred
Concept UI M0005293
Scope note A transferase that catalyzes formation of PHOSPHOCREATINE from ATP + CREATINE. The reaction stores ATP energy as phosphocreatine. Three cytoplasmic ISOENZYMES have been identified in human tissues: the MM type from SKELETAL MUSCLE, the MB type from myocardial tissue and the BB type from nervous tissue as well as a mitochondrial isoenzyme. Macro-creatine kinase refers to creatine kinase complexed with other serum proteins.
Preferred term Creatine Kinase
Entry term(s) ADP Phosphocreatine Phosphotransferase
ATP Creatine Phosphotransferase
Creatine Phosphokinase
Creatine Phosphotransferase, ATP
Kinase, Creatine
Phosphocreatine Phosphotransferase, ADP
Phosphokinase, Creatine
Phosphotransferase, ADP Phosphocreatine
Phosphotransferase, ATP Creatine
Macro-Creatine Kinase - Narrower
Concept UI M0483994
Preferred term Macro-Creatine Kinase
Entry term(s) Macro Creatine Kinase



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