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Descriptor English: rac1 GTP-Binding Protein
Descriptor Spanish: Proteína de Unión al GTP rac1
Descriptor proteína de unión al GTP rac1
Entry term(s) proteína TC-25 de unión a GTP
proteína TC-25 de unión al GTP
Scope note: Proteína de unión al GTP rac que interviene en la regulación de los filamentos de actina en la membrana plasmática. Controla el desarrollo de los filópodos y los lamelípodos de las células, influyendo así en la motilidad y la adhesión celular. También interviene en la activación de la NADPH OXIDASA. Esta enzima fue clasificada anteriormente como EC 3.6.1.47.
Descriptor Portuguese: Proteínas rac1 de Ligação ao GTP
Descriptor French: Protéine G rac1
Entry term(s): GTP-Binding Protein, TC-25
GTP-Binding Protein, rac1
TC 25 GTP Binding Protein
TC-25 GTP-Binding Protein
rac1 GTP Binding Protein
rac1 Protein
ras Related C3 Botulinum Toxin Substrate 1
ras-Related C3 Botulinum Toxin Substrate 1
Tree number(s): D08.811.277.040.330.300.400.700.100.500
D12.776.157.325.515.700.100.100
D12.776.476.338.400.700.100.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D020830
Scope note: A rac GTP-binding protein involved in regulating actin filaments at the plasma membrane. It controls the development of filopodia and lamellipodia in cells and thereby influences cellular motility and adhesion. It is also involved in activation of NADPH OXIDASES. This enzyme was formerly listed as EC 3.6.1.47.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.6.5.2
Previous Indexing: G-Proteins (1991-1999)
Public MeSH Note: 2000; RAC1 GENE PRODUCT was indexed under G-PROTEINS 1991-1999 & PROTEINS 1989-1990
History Note: 2000; for RAC1 GENE PRODUCT use RAC GTP-BINDING PROTEINS (NM) 1989-1999
DeCS ID: 34431
Unique ID: D020830
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2000/01/01
Date of Entry: 1999/11/03
Revision Date: 2017/07/13
rac1 GTP-Binding Protein - Preferred
Concept UI M0328243
Scope note A rac GTP-binding protein involved in regulating actin filaments at the plasma membrane. It controls the development of filopodia and lamellipodia in cells and thereby influences cellular motility and adhesion. It is also involved in activation of NADPH OXIDASES. This enzyme was formerly listed as EC 3.6.1.47.
Preferred term rac1 GTP-Binding Protein
Entry term(s) GTP-Binding Protein, TC-25
GTP-Binding Protein, rac1
TC 25 GTP Binding Protein
TC-25 GTP-Binding Protein
rac1 GTP Binding Protein
rac1 Protein
ras Related C3 Botulinum Toxin Substrate 1
ras-Related C3 Botulinum Toxin Substrate 1



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