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Descriptor English: Neuregulin-1
Descriptor Spanish: Neurregulina-1
Descriptor neurregulina-1
Entry term(s) factor de crecimiento glial
factor de diferenciación neu
herregulina
proteína NDF
proteína NRG1
Scope note: Factor peptídico identificado originalmente por su capacidad para estimular la fosforilación del receptor erbB-2 (RECEPTOR ERBB-2). Es un ligando para el receptor erbB-3 (RECEPTOR ERBB-3) y el receptor erbB-4. Se dan formas variantes de la NEURREGULINA-1 por medio de un corte y empalme alternativo de su ARN mensajero.
Descriptor Portuguese: Neuregulina-1
Descriptor French: Neuréguline-1
Entry term(s): Differentiation Factor, neu
GGF Protein
Glial Growth Factor
Heregulin
NDF Protein
NRG1 Protein
Neuregulin 1
neu Differentiation Factor
Tree number(s): D12.644.276.860.550.750
D12.776.467.860.550.750
D12.776.631.600.550.750
D23.529.850.550.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D020890
Scope note: A peptide factor originally identified by its ability to stimulate the phosphorylation the erbB-2 receptor (RECEPTOR, ERBB-2). It is a ligand for the erbB-3 receptor (RECEPTOR, ERBB-3) and the erbB-4 receptor. Variant forms of NEUREGULIN-1 occur through alternative splicing of its mRNA.
Annotation: do not confuse entry term GLIAL GROWTH FACTOR with GLIA MATURATION FACTOR
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Glycoproteins (1986-1999)
Nerve Tissue Proteins (1980-1999)
Public MeSH Note: 2000; NEUREGULIN-1 was indexed under GLYCOPROTEINS 1993-1999; GLIAL GROWTH FACTOR was indexed under NERVE TISSUE PROTEINS 1980-1999
History Note: 2000; use NEUREGULIN-1 (NM) 1993-1999; for GLIAL GROWTH FACTOR use GLIA MATURATION FACTOR (NM) 1980-1999
DeCS ID: 34465
Unique ID: D020890
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2000/01/01
Date of Entry: 1999/11/04
Revision Date: 2015/11/24
Neuregulin-1 - Preferred
Concept UI M0328212
Scope note A peptide factor originally identified by its ability to stimulate the phosphorylation the erbB-2 receptor (RECEPTOR, ERBB-2). It is a ligand for the erbB-3 receptor (RECEPTOR, ERBB-3) and the erbB-4 receptor. Variant forms of NEUREGULIN-1 occur through alternative splicing of its mRNA.
Preferred term Neuregulin-1
Entry term(s) NDF Protein
NRG1 Protein
Neuregulin 1
Glial Growth Factor - Narrower
Concept UI M0063177
Preferred term Glial Growth Factor
Entry term(s) GGF Protein
Heregulin - Narrower
Concept UI M0332444
Preferred term Heregulin
neu Differentiation Factor - Narrower
Concept UI M0137305
Preferred term neu Differentiation Factor
Entry term(s) Differentiation Factor, neu



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