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Descriptor English: Chimerin 1
Descriptor Spanish: Quimerina 1
Descriptor quimerina 1
Entry term(s) proteína arhGAP2
proteína rhoGAP2
quimerina alfa
quimerina alfa 1
quimerina alfa 2
quimerina n
Scope note: Proteína activadora de GTPasa que es específica para las PROTEÍNAS DE UNIÓN A GTP RAC. Se expresa principalmente en el cerebro y puede estar implicada en las transducción de señales. La forma de QUIMERINA 1 (quimerina alfa 2) ayustada alternativamente contiene un dominio de homología src adicional y se expresa tanto en el cerebro como en los testículos.
Descriptor Portuguese: Quimerina 1
Descriptor French: Chimérine-1
Entry term(s): Chimaerin 1
Chimaerin, alpha-1
Chimaerin, alpha-2
Chimerin, alpha-1
Chimerin, alpha-2
alpha 1 Chimaerin
alpha 1 Chimerin
alpha 2 Chimaerin
alpha 2 Chimerin
alpha Chimaerin
alpha Chimerin
alpha-1 Chimaerin
alpha-1 Chimerin
alpha-2 Chimaerin
alpha-2 Chimerin
alpha-Chimaerin
alpha-Chimerin
alpha1 Chimaerin
alpha1-Chimaerin
arhGAP2 Protein
n Chimaerin
n-Chimaerin
n-Chimerin
rhoGAP2 Protein
Tree number(s): D12.644.360.325.150.100.200
D12.776.476.325.150.100.200
D12.776.631.124.200
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D020848
Scope note: A GTPase activating protein that is specific for RAC GTP-BINDING PROTEINS. It is expressed primarily in the brain and may be involved in signal transduction. The alternatively spliced form of CHIMERIN 1 (alpha-2 Chimerin) contains an additional src homology domain and is expressed in both the brain and testes.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Nerve Tissue Proteins (1991-1999)
Public MeSH Note: 2000; N-CHIMAERIN (now CHIMERIN 1) was indexed under NERVE TISSUE PROTEINS 1990-1999; ALPHA1-CHIMAERIN was indexed under PROTEINS 1996-1999
History Note: 2000; use CHIMERIN 1 (NM) 1990-1999; for ALPHA1-CHIMAERIN use GTPASE-ACTIVATING PROTEINS (NM) 1996-1999
DeCS ID: 34484
Unique ID: D020848
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2000/01/01
Date of Entry: 1999/11/03
Revision Date: 2015/11/23
Chimerin 1 - Preferred
Concept UI M0328168
Scope note A GTPase activating protein that is specific for RAC GTP-BINDING PROTEINS. It is expressed primarily in the brain and may be involved in signal transduction. The alternatively spliced form of CHIMERIN 1 (alpha-2 Chimerin) contains an additional src homology domain and is expressed in both the brain and testes.
Preferred term Chimerin 1
Entry term(s) Chimaerin 1
Chimaerin, alpha-1
Chimerin, alpha-1
alpha 1 Chimaerin
alpha 1 Chimerin
alpha Chimaerin
alpha Chimerin
alpha-1 Chimaerin
alpha-1 Chimerin
alpha-Chimaerin
alpha-Chimerin
alpha1 Chimaerin
alpha1-Chimaerin
arhGAP2 Protein
n Chimaerin
n-Chimaerin
n-Chimerin
rhoGAP2 Protein
alpha-2 Chimerin - Narrower
Concept UI M0331682
Preferred term alpha-2 Chimerin
Entry term(s) Chimaerin, alpha-2
Chimerin, alpha-2
alpha 2 Chimaerin
alpha 2 Chimerin
alpha-2 Chimaerin



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