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Descriptor English: p120 GTPase Activating Protein
Descriptor Spanish: Proteína Activadora de GTPasa p120
Descriptor proteína p120 activadora de GTPasa
Entry term(s) proteína p100-GAP
proteína p120 GAP
proteína p125 GAP
Scope note: Proteína RAS activadora de GTP, de 120 kDa, que se une a las fosfoproteínas de tirosina por medio de los dominios SH2. La variante de corte y empalme del ARN de 100 kDa (proteína p100 GAP) se expresa en la placenta.
Descriptor Portuguese: Proteína p120 Ativadora de GTPase
Descriptor French: Protéine p120 d'activation de la ras GTPase
Entry term(s): GAP, p100
GAP, p120
GAP, p125
p100 GAP
p100 GAP Protein
p100-GAP Protein
p120 GAP
p120 GAP Protein
p120-GAP Protein
p120rasGAP
p125 GAP
p125 GAP Protein
p125-GAP Protein
Tree number(s): D12.644.360.325.150.500.500
D12.776.476.325.150.500.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D020729
Scope note: A 120-kDa RAS GTPase-activating protein that binds to tyrosine phosphoproteins through its SH2 domains. The 100-kDa RNA-splicing variant (p100 GAP protein) is expressed in placenta.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Proteins (1989-1999)
Public MeSH Note: 2000; P120-GAP PROTEIN was indexed under PROTEINS 1994-1999; P100-GAP PROTEIN was indexed under PROTEINS 1995-1999; P120RASGAP & P125 GAP were indexed under PROTEINS 1996-1999
History Note: 2000; for P120-GAP PROTEIN use GTPASE ACTIVATING PROTEINS (NM) 1994-1999; for P100-GAP PROTEIN use GTPASE ACTIVATING PROTEINS (NM) 1995-1999; for P120RASGAP & P125 GAP use GTPASE ACTIVATING PROTEINS (NM) 1996-1999
DeCS ID: 34486
Unique ID: D020729
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2000/01/01
Date of Entry: 1999/11/05
Revision Date: 2015/11/24
p120 GTPase Activating Protein - Preferred
Concept UI M0328218
Scope note A 120-kDa RAS GTPase-activating protein that binds to tyrosine phosphoproteins through its SH2 domains. The 100-kDa RNA-splicing variant (p100 GAP protein) is expressed in placenta.
Preferred term p120 GTPase Activating Protein
Entry term(s) GAP, p120
GAP, p125
p120 GAP
p120 GAP Protein
p120-GAP Protein
p120rasGAP
p125 GAP
p125 GAP Protein
p125-GAP Protein
p100-GAP Protein - Narrower
Concept UI M0156259
Preferred term p100-GAP Protein
Entry term(s) GAP, p100
p100 GAP
p100 GAP Protein



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