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Descriptor English: RNA, Small Nucleolar
Descriptor Spanish: ARN Nucleolar Pequeño
Descriptor ARN nucleolar pequeño
Entry term(s) snoRNA
Scope note: ARN nucleares pequeños que participan en el procesamiento del ARN pre-ribosómico en el nucléolo. La caja C/D que contiene snoRNA (U14, U15, U16, U20, U21 y U24-U63) dirige la metilación específica del sitio de diversas porciones de ribosa. La caja H/ACA que contiene snoRNA (E2, E3, U19, U23 y U64-U72) dirige la conversión de uridinas específicas en pseudouridina. La escisión en sitios específicos que se produce en los ARN ribosómicos maduros es dirigida por los snoRNA U3, U8, U14, U22 y los ARN nucleolares pequeños (snoRNA) componentes de la ribonucleasa procesadora del ARN mitocondrial (RNasaMRP) y la ribonucleasa P (RNasa P).
Descriptor Portuguese: RNA Nucleolar Pequeno
Descriptor French: Petit ARN nucléolaire
Entry term(s): Small Nucleolar RNA
snoRNA
Tree number(s): D13.444.735.628.818.800
D13.444.735.790.552.937.800
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D020537
Scope note: Small nuclear RNAs that are involved in the processing of pre-ribosomal RNA in the nucleolus. Box C/D containing snoRNAs (U14, U15, U16, U20, U21 and U24-U63) direct site-specific methylation of various ribose moieties. Box H/ACA containing snoRNAs (E2, E3, U19, U23, and U64-U72) direct the conversion of specific uridines to pseudouridine. Site-specific cleavages resulting in the mature ribosomal RNAs are directed by snoRNAs U3, U8, U14, U22 and the snoRNA components of RNase MRP and RNase P.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Cell Nucleolus (1975-1999)
RNA (1975-1985)
RNA, Small Nuclear (1986-1999)
Public MeSH Note: 2000
History Note: 2000
DeCS ID: 34511
Unique ID: D020537
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2000/01/01
Date of Entry: 1999/11/03
Revision Date: 2010/06/25
RNA, Small Nucleolar - Preferred
Concept UI M0328073
Scope note Small nuclear RNAs that are involved in the processing of pre-ribosomal RNA in the nucleolus. Box C/D containing snoRNAs (U14, U15, U16, U20, U21 and U24-U63) direct site-specific methylation of various ribose moieties. Box H/ACA containing snoRNAs (E2, E3, U19, U23, and U64-U72) direct the conversion of specific uridines to pseudouridine. Site-specific cleavages resulting in the mature ribosomal RNAs are directed by snoRNAs U3, U8, U14, U22 and the snoRNA components of RNase MRP and RNase P.
Preferred term RNA, Small Nucleolar
Entry term(s) Small Nucleolar RNA
snoRNA



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