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Descriptor English: Comet Assay
Descriptor Spanish: Ensayo Cometa
Descriptor análisis de cometas
Entry term(s) electroforesis sobre gel de célula individual
ensayo cometa alcalino
ensayo de electroforesis sobre gel de célula individual alcalina
Scope note: Técnica genotoxicológica para medir el daño del ADN en una célula individual, empleando la electroforesis sobre gel en células aisladas. Durante la electroforesis, los fragmentos del ADN adoptan una forma de 'cometa con cola' y pueden ser detectados con un sistema de análisis de imagen. Las condiciones alcalinas del ensayo facilitan la detección sensible de daños de una sola cadena.
Descriptor Portuguese: Ensaio Cometa
Descriptor French: Test des comètes
Entry term(s): Alkaline Comet Assay
Alkaline Comet Assays
Alkaline Single Cell Gel Electrophoresis Assay
Alkaline Single-Cell Gel Electrophoresis Assay
Assay, Alkaline Comet
Assay, Comet
Assays, Alkaline Comet
Assays, Comet
Comet Assay, Alkaline
Comet Assays
Comet Assays, Alkaline
Electrophoreses, Single-Cell Gel
Electrophoresis, Gel, Single-Cell
Electrophoresis, Single-Cell Gel
Gel Electrophoreses, Single-Cell
Gel Electrophoresis, Single Cell
Gel Electrophoresis, Single-Cell
Single-Cell Gel Electrophoreses
Single-Cell Gel Electrophoresis
Tree number(s): E05.196.401.153.150
E05.301.300.100.150
E05.393.560.150
E05.940.560.150
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D020552
Scope note: A genotoxicological technique for measuring DNA damage in an individual cell using single-cell gel electrophoresis. Cell DNA fragments assume a "comet with tail" formation on electrophoresis and are detected with an image analysis system. Alkaline assay conditions facilitate sensitive detection of single-strand damage.
Allowable Qualifiers: CL classification
EC economics
ES ethics
HI history
IS instrumentation
MT methods
SN statistics & numerical data
ST standards
TD trends
VE veterinary
Previous Indexing: Electrophoresis (1990-1999)
Electrophoresis, Agar Gel (1990-1999)
Mutagenicity Tests (1992-1999)
Public MeSH Note: 2000
History Note: 2000
Related: DNA Damage MeSH
DeCS ID: 34538
Unique ID: D020552
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2000/01/01
Date of Entry: 1999/11/03
Revision Date: 2008/07/08
Comet Assay - Preferred
Concept UI M0328445
Scope note A genotoxicological technique for measuring DNA damage in an individual cell using single-cell gel electrophoresis. Cell DNA fragments assume a "comet with tail" formation on electrophoresis and are detected with an image analysis system. Alkaline assay conditions facilitate sensitive detection of single-strand damage.
Preferred term Comet Assay
Entry term(s) Assay, Comet
Assays, Comet
Comet Assays
Electrophoreses, Single-Cell Gel
Electrophoresis, Gel, Single-Cell
Electrophoresis, Single-Cell Gel
Gel Electrophoreses, Single-Cell
Gel Electrophoresis, Single Cell
Gel Electrophoresis, Single-Cell
Single-Cell Gel Electrophoreses
Single-Cell Gel Electrophoresis
Alkaline Comet Assay - Narrower
Concept UI M0331454
Preferred term Alkaline Comet Assay
Entry term(s) Alkaline Comet Assays
Alkaline Single Cell Gel Electrophoresis Assay
Alkaline Single-Cell Gel Electrophoresis Assay
Assay, Alkaline Comet
Assays, Alkaline Comet
Comet Assay, Alkaline
Comet Assays, Alkaline



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