Search
Descriptor English: Focal Adhesions
Descriptor Spanish: Adhesiones Focales
Descriptor adhesiones focales
Entry term(s) adherencias focales
contactos focales
placas de adhesión
uniones adherentes célula-matriz
Scope note: Puntos de anclaje de la célula a un sustrato acelular. Están compuestos por un área especializada de la membrana plasmática donde terminan haces del CITOESQUELETO DE ACTINA y se fijan a los conectores transmembrana, INTEGRINAS, que a su vez se unen, a través de sus dominios extracelulares, a las PROTEÍNAS DE LA MATRIZ EXTRACELULAR.
Descriptor Portuguese: Adesões Focais
Descriptor French: Contacts focaux
Entry term(s): Adherens Junction, Cell-Matrix
Adherens Junctions, Cell-Matrix
Adhesion Plaque
Adhesion Plaques
Adhesion, Focal
Adhesions, Focal
Cell Matrix Adherens Junctions
Cell-Matrix Adherens Junction
Cell-Matrix Adherens Junctions
Contact, Focal
Contacts, Focal
Focal Adhesion
Focal Contact
Focal Contacts
Junction, Cell-Matrix Adherens
Junctions, Cell-Matrix Adherens
Plaque, Adhesion
Plaques, Adhesion
Tree number(s): A11.284.149.165.165.285
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D022001
Scope note: An anchoring junction of the cell to a non-cellular substrate. It is composed of a specialized area of the plasma membrane where bundles of the ACTIN CYTOSKELETON terminate and attach to the transmembrane linkers, INTEGRINS, which in turn attach through their extracellular domains to EXTRACELLULAR MATRIX PROTEINS.
Allowable Qualifiers: CH chemistry
CL classification
DE drug effects
EN enzymology
GE genetics
IM immunology
ME metabolism
MI microbiology
PA pathology
PH physiology
PS parasitology
RE radiation effects
TR transplantation
UL ultrastructure
VI virology
Previous Indexing: Cell Adhesion (1986-2000)
Extracellular Matrix (1986-2000)
Public MeSH Note: 2001
History Note: 2001
Related: Cell Adhesion MeSH
DeCS ID: 35265
Unique ID: D022001
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2001/01/01
Date of Entry: 2000/06/21
Revision Date: 2011/07/01
Focal Adhesions - Preferred
Concept UI M0356350
Scope note An anchoring junction of the cell to a non-cellular substrate. It is composed of a specialized area of the plasma membrane where bundles of the ACTIN CYTOSKELETON terminate and attach to the transmembrane linkers, INTEGRINS, which in turn attach through their extracellular domains to EXTRACELLULAR MATRIX PROTEINS.
Preferred term Focal Adhesions
Entry term(s) Adherens Junction, Cell-Matrix
Adherens Junctions, Cell-Matrix
Adhesion Plaque
Adhesion Plaques
Adhesion, Focal
Adhesions, Focal
Cell Matrix Adherens Junctions
Cell-Matrix Adherens Junction
Cell-Matrix Adherens Junctions
Contact, Focal
Contacts, Focal
Focal Adhesion
Focal Contact
Focal Contacts
Junction, Cell-Matrix Adherens
Junctions, Cell-Matrix Adherens
Plaque, Adhesion
Plaques, Adhesion



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey