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Descriptor English: Protein Footprinting
Descriptor Spanish: Huella de Proteína
Descriptor huella de proteína
Entry term(s) huellas de proteínas
Scope note: Método para la determinación de puntos de contacto entre proteínas interactivas o sitios de enlace de proteínas a ácidos nucleicos. Para la huella de proteína se utiliza un reactivo o proteasa que corta la proteína. La segmentación proteica es inhibida cuando las proteínas, o ácidos nucleicos y proteína, entran en contacto mutuamente. Tras finalizar la reacción de corte, los fragmentos restantes de péptidos son analizados por electroforesis.
Descriptor Portuguese: Pegadas de Proteínas
Descriptor French: Prise d'empreintes protéiques
Entry term(s): Footprint, Protein
Footprinting, Protein
Footprints, Protein
Protein Footprint
Protein Footprints
Tree number(s): E05.196.700.690
E05.393.760.705.685.690
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D023302
Scope note: A method for determining points of contact between interacting proteins or binding sites of proteins to nucleic acids. Protein footprinting utilizes a protein cutting reagent or protease. Protein cleavage is inhibited where the proteins, or nucleic acids and protein, contact each other. After completion of the cutting reaction, the remaining peptide fragments are analyzed by electrophoresis.
Allowable Qualifiers: AE adverse effects
CL classification
EC economics
ES ethics
HI history
IS instrumentation
MT methods
SN statistics & numerical data
ST standards
TD trends
VE veterinary
Public MeSH Note: 2001
History Note: 2001
DeCS ID: 35399
Unique ID: D023302
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2001/01/01
Date of Entry: 2000/07/06
Revision Date: 2002/07/03
Protein Footprinting - Preferred
Concept UI M0361105
Scope note A method for determining points of contact between interacting proteins or binding sites of proteins to nucleic acids. Protein footprinting utilizes a protein cutting reagent or protease. Protein cleavage is inhibited where the proteins, or nucleic acids and protein, contact each other. After completion of the cutting reaction, the remaining peptide fragments are analyzed by electrophoresis.
Preferred term Protein Footprinting
Entry term(s) Footprinting, Protein
Protein Footprints - Related but not broader or narrower
Concept UI M0361106
Preferred term Protein Footprints
Entry term(s) Footprint, Protein
Footprints, Protein
Protein Footprint



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