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Descriptor English: Cysteinyldopa
Descriptor Spanish: Cisteinildopa
Descriptor cisteinildopa
Scope note: Se encuentra en grandes cantidades en la orina y plasma de los pacientes con melanoma. Por ello se utiliza para el diagnóstico del melanoma y para la detección de metástasis posoperatorias. Se piensa que se forma por hidrólisis enzimática rápida de la 5-5-glutaniondopa de las células productoras de melanina.
Descriptor Portuguese: Cisteinildopa
Descriptor French: 5-((2-Amino-2-carboxyéthyl)sulfanyl)-3-hydroxy-tyrosine
Entry term(s): 5 S Cysteinyldopa
5-S-Cysteinyldopa
Tree number(s): D02.092.311.200.180
D02.455.426.559.389.657.166.175.200.180
D02.886.030.230.330
D12.125.072.050.685.400.180
D12.125.072.050.875.130.180
D12.125.166.230.330
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D003548
Scope note: Found in large amounts in the plasma and urine of patients with malignant melanoma. It is therefore used in the diagnosis of melanoma and for the detection of postoperative metastases. Cysteinyldopa is believed to be formed by the rapid enzymatic hydrolysis of 5-S-glutathionedopa found in melanin-producing cells.
Annotation: /biosyn /physiol permitted
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Registry Number: 19641-92-0
CAS Type 1 Name: L-Tyrosine, 3-((2-amino-2-carboxyethyl)thio)-5-hydroxy-, (R)-
Previous Indexing: Cysteine (1966-1976)
Dopa (1966-1976)
Public MeSH Note: 91; was see under DOPA 1977-90
History Note: 91(77); was see under DOPA 1977-90
DeCS ID: 3566
Unique ID: D003548
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1976/04/27
Revision Date: 2018/06/30
Cysteinyldopa - Preferred
Concept UI M0005549
Scope note Found in large amounts in the plasma and urine of patients with malignant melanoma. It is therefore used in the diagnosis of melanoma and for the detection of postoperative metastases. Cysteinyldopa is believed to be formed by the rapid enzymatic hydrolysis of 5-S-glutathionedopa found in melanin-producing cells.
Preferred term Cysteinyldopa
Entry term(s) 5 S Cysteinyldopa
5-S-Cysteinyldopa



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