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Descriptor English: HMGA1b Protein
Descriptor Spanish: Proteína HMGA1b
Descriptor proteína HMGA1b
Scope note: Proteína que contiene SECUENCIAS AT-HOOK, que se une a las ramas menores de las regiones de ADN ricas en AT. Se trata de una forma truncada de la proteína HMGA1a que se produce por ayuste alternativo del gen HMGA1. Puede actuar como proteína de unión a la cromatina arquitectural que está involucrada en la regulación transcripcional.
Descriptor Portuguese: Proteína HMGA1b
Descriptor French: Protéine HMGA1b
Entry term(s): AT Hook 1b Protein, High Mobility Group
AT-Hook 1b Protein, High Mobility Group
HMGY Protein
Tree number(s): D12.776.260.312.750
D12.776.660.235.400.500.200
D12.776.664.235.400.500.200
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D025742
Scope note: An AT-hook motif-containing protein (AT-HOOK MOTIFS) that binds to the minor grove of AT-rich regions of DNA. It is a truncated form of HMGA1a protein that is produced by alternative-splicing of the HMGA1 gene. It may function as an architectural chromatin binding protein that is involved in transcriptional regulation.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: 124543-08-4
Previous Indexing: High Mobility Group Proteins (1993-2001)
Transcription Factors (1993-2001)
Public MeSH Note: 2002; HMGY PROTEIN was indexed under HIGH MOBILITY GROUP PROTEINS & TRANSCRIPTION FACTORS 1993-2001
History Note: 2002; for HMGY PROTEIN use HMGA1B PROTEIN (NM) 1993-2001
DeCS ID: 36200
Unique ID: D025742
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2002/01/01
Date of Entry: 2001/07/25
Revision Date: 2013/07/09
HMGA1b Protein - Preferred
Concept UI M0212171
Scope note An AT-hook motif-containing protein (AT-HOOK MOTIFS) that binds to the minor grove of AT-rich regions of DNA. It is a truncated form of HMGA1a protein that is produced by alternative-splicing of the HMGA1 gene. It may function as an architectural chromatin binding protein that is involved in transcriptional regulation.
Preferred term HMGA1b Protein
Entry term(s) AT Hook 1b Protein, High Mobility Group
AT-Hook 1b Protein, High Mobility Group
HMGY Protein



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