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Descriptor English: HMGA1a Protein
Descriptor Spanish: Proteína HMGA1a
Descriptor proteína HMGA1a
Entry term(s) proteína tipo HMG I
Scope note: Proteina que contiene SECUENCIAS AT-HOOK de 11 KD, que se une a las ramas menores de las regiones de ADN ricas en AT. Es el producto de longitud completa del gen HMGA1 emsamblado de forma alternativa y puede funcionar como una proteina unida a la cromatina estructural, que está implicada en la regulación transcripcional.
Descriptor Portuguese: Proteína HMGA1a
Descriptor French: Protéine HMGA1a
Entry term(s): AT Hook 1a Protein, High Mobility Group
AT-Hook 1a Protein, High Mobility Group
HMG I Type Protein
HMG I Y Phosphoprotein
HMG I-Type Protein
HMG I-Y Phosphoprotein
HMG-I(Y) Protein
HMGI Protein
HMGI(Y) Gene Product
High Mobility Group I(Y) Protein
Phosphoprotein, HMG I-Y
Tree number(s): D12.776.260.312.500
D12.776.660.235.400.500.100
D12.776.664.235.400.500.100
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D025741
Scope note: An 11-kDa AT-hook motif-containing (AT-HOOK MOTIFS) protein that binds to the minor grove of AT-rich regions of DNA. It is the full-length product of the alternatively-spliced HMGA1 gene and may function as an architectural chromatin binding protein that is involved in transcriptional regulation.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: 124544-67-8
Previous Indexing: High Mobility Group Proteins (1993-2001)
Public MeSH Note: 2002; HMG I-TYPE PROTEIN was indexed under HIGH MOBILITY GROUP PROTEINS & TRANSCRIPTION FACTORS 1993-2001
History Note: 2002; for HMG I-TYPE PROTEIN use HMGA1A PROTEIN (NM) 1993-2001
DeCS ID: 36199
Unique ID: D025741
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2002/01/01
Date of Entry: 2001/07/25
Revision Date: 2004/07/07
HMGA1a Protein - Preferred
Concept UI M0375723
Scope note An 11-kDa AT-hook motif-containing (AT-HOOK MOTIFS) protein that binds to the minor grove of AT-rich regions of DNA. It is the full-length product of the alternatively-spliced HMGA1 gene and may function as an architectural chromatin binding protein that is involved in transcriptional regulation.
Preferred term HMGA1a Protein
Entry term(s) AT Hook 1a Protein, High Mobility Group
AT-Hook 1a Protein, High Mobility Group
HMG I Type Protein
HMG I Y Phosphoprotein
HMG I-Type Protein
HMG I-Y Phosphoprotein
HMG-I(Y) Protein
HMGI Protein
HMGI(Y) Gene Product
High Mobility Group I(Y) Protein
Phosphoprotein, HMG I-Y



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