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Descriptor English: Collagen Type IV
Descriptor Spanish: Colágeno Tipo IV
Descriptor colágeno de tipo IV
Scope note: Colágeno no fibrilar que se encuentra en la estructura de la MEMBRANA BASAL. Las moléculas del colágeno de tipo IV se unen para formar una red de tipo laminar que interviene en el mantenimiento de la integridad estructural de las membranas basales. La forma predominante de la proteína consta de dos subunidades alfa 1 (IV) y de una subunidad alfa 2 (IV); sin embargo, en el heterotrímero pueden incorporarse al menos seis subunidades alfa diferentes.
Descriptor Portuguese: Colágeno Tipo IV
Descriptor French: Collagène de type IV
Entry term(s): 7S Collagen
Collagen Type IV, alpha1 Chain
Collagen Type IV, alpha1 Subunit
Collagen Type IV, alpha2 Chain
Collagen Type IV, alpha2 Subunit
Collagen alpha1(IV)
Collagen, 7S
Collagen, Type IV
Procollagen Type IV
Procollagen, Type IV
Type IV (Basement Membrane) Collagen
Type IV Collagen
Type IV Procollagen
alpha1(IV) collagen
Tree number(s): D12.776.860.300.250.400.100
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D024141
Scope note: A non-fibrillar collagen found in the structure of BASEMENT MEMBRANE. Collagen type IV molecules assemble to form a sheet-like network which is involved in maintaining the structural integrity of basement membranes. The predominant form of the protein is comprised of two alpha1(IV) subunits and one alpha2(IV) subunit, however, at least six different alpha subunits can be incorporated into the heterotrimer.
Annotation: precursors: coord IM with PROCOLLAGEN (IM)
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Collagen (1978-2001)
Public MeSH Note: 2002; see COLLAGEN 1990-2001; for PROCOLLAGEN TYPE IV see PROCOLLAGEN 1982-2001; for 7S COLLAGEN see COLLAGEN 1982-2001
History Note: 2002; use COLLAGEN 1990-2001; for PROCOLLAGEN TYPE IV use PROCOLLAGEN 1982-2001; for 7S COLLAGEN use COLLAGEN 1982-2001
Related: Porencephaly MeSH
DeCS ID: 36246
Unique ID: D024141
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2002/01/01
Date of Entry: 2001/07/25
Revision Date: 2014/06/13
Collagen Type IV - Preferred
Concept UI M0004779
Scope note A non-fibrillar collagen found in the structure of BASEMENT MEMBRANE. Collagen type IV molecules assemble to form a sheet-like network which is involved in maintaining the structural integrity of basement membranes. The predominant form of the protein is comprised of two alpha1(IV) subunits and one alpha2(IV) subunit, however, at least six different alpha subunits can be incorporated into the heterotrimer.
Preferred term Collagen Type IV
Entry term(s) Collagen, Type IV
Type IV (Basement Membrane) Collagen
Type IV Collagen
Collagen Type IV, alpha1 Subunit - Narrower
Concept UI M0369423
Preferred term Collagen Type IV, alpha1 Subunit
Entry term(s) Collagen Type IV, alpha1 Chain
Collagen alpha1(IV)
alpha1(IV) collagen
Procollagen Type IV - Narrower
Concept UI M0017627
Preferred term Procollagen Type IV
Entry term(s) Procollagen, Type IV
Type IV Procollagen
7S Collagen - Narrower
Concept UI M0004772
Scope note A stable peptide fragment originating from the N-terminal domain of collagen type IV.
Preferred term 7S Collagen
Entry term(s) Collagen, 7S
Collagen Type IV, alpha2 Subunit - Narrower
Concept UI M0369424
Preferred term Collagen Type IV, alpha2 Subunit
Entry term(s) Collagen Type IV, alpha2 Chain



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