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Descriptor English: Sodium Channel Blockers
Descriptor Spanish: Bloqueadores de los Canales de Sodio
Descriptor bloqueantes de los canales del sodio
Entry term(s) bloqueador de los canales de sodio
inhibidor de los canales de sodio
Scope note: Drogas que actúan inhibiendo en paso del sodio a traves de la membrana celular. El bloqueo de los canales de sodio retarda la velocidad y amplitud de la despolarización rápida inicial, reduce la excitabilidad, y disminuye la velocidad de conducción.
Descriptor Portuguese: Bloqueadores dos Canais de Sódio
Descriptor French: Bloqueurs de canaux sodiques
Entry term(s): Blocker, Sodium Channel
Channel Blocker, Sodium
Channel Blockers, Sodium
Channel Inhibitor, Sodium
Channel Inhibitors, Sodium
Inhibitor, Sodium Channel
Inhibitors, Sodium Channel
Sodium Channel Blocker
Sodium Channel Inhibitor
Sodium Channel Inhibitors
Tree number(s): D27.505.519.562.750
D27.505.954.411.720
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D026941
Scope note: A class of drugs that act by inhibition of sodium influx through cell membranes. Blockade of sodium channels slows the rate and amplitude of initial rapid depolarization, reduces cell excitability, and reduces conduction velocity.
Annotation: coordinate with DIURETICS if pertinent
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Previous Indexing: Ion Channels (1982-1988)
Sodium Channels/antagonists & inhibitors (1988-2001)
Public MeSH Note: 2002
History Note: 2002
Entry Version: NA CHANNEL BLOCK
Related: Anti-Arrhythmia Agents MeSH
DeCS ID: 36264
Unique ID: D026941
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2002/01/01
Date of Entry: 2001/07/25
Revision Date: 2020/05/27
Sodium Channel Blockers - Preferred
Concept UI M0379271
Scope note A class of drugs that act by inhibition of sodium influx through cell membranes. Blockade of sodium channels slows the rate and amplitude of initial rapid depolarization, reduces cell excitability, and reduces conduction velocity.
Preferred term Sodium Channel Blockers
Entry term(s) Blocker, Sodium Channel
Channel Blocker, Sodium
Channel Blockers, Sodium
Channel Inhibitor, Sodium
Channel Inhibitors, Sodium
Inhibitor, Sodium Channel
Inhibitors, Sodium Channel
Sodium Channel Blocker
Sodium Channel Inhibitor
Sodium Channel Inhibitors



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