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Descriptor English: Sodium Potassium Chloride Symporter Inhibitors
Descriptor Spanish: Inhibidores del Simportador de Cloruro Sódico y Cloruro Potásico
Descriptor inhibidores de los simportadores del cloruro de sodio-potasio
Entry term(s) diurético del asa
inhibidores del simportador de NaCl y KCl
Scope note: Fármacos que inhiben a los SIMPORTADORES DE CLORURO SÓDICO Y CLORURO POTÁSICO que están concentrados en la rama ascendente, a nivel de la unión del ASA DE HENLE y la PORCIÓN DISTAL DE LOS TÚBULOS RENALES. Estos compuestos actúan como DIURÉTICOS. Su uso excesivo se asocia a HIPOPOTASEMIA e HIPERGLUCEMIA.
Descriptor Portuguese: Inibidores de Simportadores de Cloreto de Sódio e Potássio
Descriptor French: Inhibiteurs du symport chlorure potassium sodium
Entry term(s): Bumetanide Sensitive Na K Cl Transporter Inhibitors
Bumetanide Sensitive Na-K-Cl-Transporter Inhibitors
Ceiling Diuretics, High
Diuretic, Loop
Diuretics, High Ceiling
Diuretics, Loop
High Ceiling Diuretics
Inhibitors, Na-K-CL Symporter
Loop Diuretic
Loop Diuretics
Na K CL Symporter Inhibitors
Na-K-CL Symporter Inhibitors
Sodium Potassium Chloride Cotransporter Inhibitors
Symporter Inhibitors, Na-K-CL
Tree number(s): D27.505.519.562.906
D27.505.696.560.500.931
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D049994
Scope note: Agents that inhibit SODIUM-POTASSIUM-CHLORIDE SYMPORTERS which are concentrated in the thick ascending limb at the junction of the LOOP OF HENLE and KIDNEY TUBULES, DISTAL. They act as DIURETICS. Excess use is associated with HYPOKALEMIA and HYPERGLYCEMIA.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Previous Indexing: Sodium-Potassium-Chloride Symporters (2002-2005)
Public MeSH Note: 2006
History Note: 2006
DeCS ID: 51201
Unique ID: D049994
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2020/05/27
Sodium Potassium Chloride Symporter Inhibitors - Preferred
Concept UI M0471884
Scope note Agents that inhibit SODIUM-POTASSIUM-CHLORIDE SYMPORTERS which are concentrated in the thick ascending limb at the junction of the LOOP OF HENLE and KIDNEY TUBULES, DISTAL. They act as DIURETICS. Excess use is associated with HYPOKALEMIA and HYPERGLYCEMIA.
Preferred term Sodium Potassium Chloride Symporter Inhibitors
Entry term(s) Bumetanide Sensitive Na K Cl Transporter Inhibitors
Bumetanide Sensitive Na-K-Cl-Transporter Inhibitors
Inhibitors, Na-K-CL Symporter
Na K CL Symporter Inhibitors
Na-K-CL Symporter Inhibitors
Sodium Potassium Chloride Cotransporter Inhibitors
Symporter Inhibitors, Na-K-CL
Loop Diuretics - Related but not broader or narrower
Concept UI M0471885
Preferred term Loop Diuretics
Entry term(s) Diuretic, Loop
Diuretics, Loop
Loop Diuretic
High Ceiling Diuretics - Related but not broader or narrower
Concept UI M0471886
Preferred term High Ceiling Diuretics
Entry term(s) Ceiling Diuretics, High
Diuretics, High Ceiling



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