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Descriptor English:

Aristolochic Acids

Descriptor Spanish:

Ácidos Aristolóquicos

Spanish from Spain

Descriptor	ácidos aristolóquicos
Scope note:	Nitrofenantrenos que se dan en las ARISTOLOCHIACEAE y otras plantas. Derivan de la stefania (APORFINA) por desdoblamiento oxidativo del anillo. El grupo nitro es un alquilante reactivo (AGENTES ALQUILANTES) que se une a macromoléculas biológicas. La ingestión por humanos se asocia con nefropatía (NEFRITIS). No hay relación con el aristolocheno de similar nombre (SESQUITERPENOS).

Descriptor Portuguese:

Ácidos Aristolóquicos

Descriptor French:

Acides aristolochiques

Tree number(s):

D02.455.426.559.847.723.089
D02.640.139
D04.615.723.089

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D034341

Scope note:

Nitro-phenanthrenes occurring in ARISTOLOCHIACEAE and other plants. They derive from stephanine (APORPHINES) by oxidative ring cleavage. The nitro group is a reactive alkylator (ALKYLATING AGENTS) that binds to biological macromolecules. Ingestion by humans is associated with nephropathy (NEPHRITIS). There is no relationship to the similar named aristolochene (SESQUITERPENES).

Allowable Qualifiers:

AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BI biosynthèse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
GE génétique
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PH physiologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine

DeCS ID:

37310

Unique ID:

D034341

Documents indexed in the Virtual Health Library (VHL):

Click here to access the VHL documents

Date Established:

2003/01/01

Date of Entry:

2002/07/02

Revision Date:

2009/08/20