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Descriptor English: Luteinizing Hormone, beta Subunit
Descriptor Spanish: Hormona Luteinizante de Subunidad beta
Descriptor subunidad beta de hormona luteinizante
Entry term(s) LHB
subunidad beta de la ICSH
subunidad beta de la LH
subunidad beta de la hormona luteinizante
subunidad beta de lutropina
Scope note: Glicopolipéptido de 15 kDa con estructura similar a la de la SUBUNIDAD BETA DE LA GONADOTROPINA CORIÓNICA PLACENTARIA excepto en los 31 aminoácidos adicionales del C-terminal de la gonadotropina coriónica beta. Para que la hormona tenga actividad biológica completa se necesita la unión no covalente de heterodímeros de una subunidad alfa y una beta. La mutación del gen de la subunidad beta de la lutropina causa HIPOGONADISMO e infertilidad.
Descriptor Portuguese: Hormônio Luteinizante Subunidade beta
Descriptor French: Sous-unité bêta de l'hormone lutéinisante
Entry term(s): ICSH, beta Subunit
LH beta
LH, beta Subunit
LH-beta
Luteinizing Hormone, beta Chain
Luteinizing Hormone, beta Polypeptide Chain
Lutropin beta
Lutropin, beta Subunit
Lutropin-beta
Tree number(s): D06.472.699.322.576.463.500
D06.472.699.631.525.343.463.500
D12.644.548.691.525.343.463.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D037101
Scope note: The beta subunit of luteinizing hormone. It is a 15-kDa glycopolypeptide with structure similar to the beta subunit of the placental chorionic gonadatropin (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN) except for the additional 31 amino acids at the C-terminal of CG-beta. Full biological activity of LH requires the non-covalently bound heterodimers of an alpha and a beta subunit. Mutation of the LHB gene causes HYPOGONADISM and infertility.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Previous Indexing: Luteinizing Hormone (1974-2002)
Public MeSH Note: 2003; LUTEINIZING HORMONE, BETA SUBUNIT was indexed under LH 1983-2002
History Note: 2003; use LUTEINIZING HORMONE, BETA SUBUNIT (NM) 1983-2002
DeCS ID: 37314
Unique ID: D037101
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2003/01/01
Date of Entry: 2002/07/03
Revision Date: 2006/07/05
Luteinizing Hormone, beta Subunit - Preferred
Concept UI M0115487
Scope note The beta subunit of luteinizing hormone. It is a 15-kDa glycopolypeptide with structure similar to the beta subunit of the placental chorionic gonadatropin (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN) except for the additional 31 amino acids at the C-terminal of CG-beta. Full biological activity of LH requires the non-covalently bound heterodimers of an alpha and a beta subunit. Mutation of the LHB gene causes HYPOGONADISM and infertility.
Preferred term Luteinizing Hormone, beta Subunit
Entry term(s) ICSH, beta Subunit
LH beta
LH, beta Subunit
LH-beta
Luteinizing Hormone, beta Chain
Luteinizing Hormone, beta Polypeptide Chain
Lutropin beta
Lutropin, beta Subunit
Lutropin-beta



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