Search
Descriptor English: Ribosomal Protein S6 Kinases, 70-kDa
Descriptor Spanish: Proteínas Quinasas S6 Ribosómicas 70-kDa
Descriptor proteína S6 cinasas ribosómicas 70-kDa
Entry term(s) p70 S6 cinasa
p70s6K
proteína S6 quinasas ribosómicas 70-kDa
Scope note: Familia de proteina S6 cinasa ribosómica. Se considera que son las principales cinasas fisiológicas de la PROTEINA S6 RIBOSÓMICA. A diferencia de las PROTEINA CINASAS S6 RIBOSÓMICAS, las proteinas de 90 kD de esta familia son sensibles a los efectos inhibidores de la RAPAMICINA y contienen un único dominio cinásico. Se les conoce como proteínas de 70 kD; sin embargo, el AYUSTE ALTERNATIVO de los ARNm para las proteinas de esta clase da lugar también a la formación de variantes de 85 kD.
Descriptor Portuguese: Proteínas Quinases S6 Ribossômicas 70-kDa
Descriptor French: Ribosomal Protein S6 Kinases, 70-kDa
Entry term(s): Ribosomal Protein S6 Kinases, 70 kDa
S6 Kinase, p70
p70 S6 Kinase
p70s6k
Tree number(s): D08.811.913.696.620.682.700.862.249
D12.776.476.563.862.249
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D038762
Scope note: A family of ribosomal protein S6 kinases that are considered the major physiological kinases for RIBOSOMAL PROTEIN S6. Unlike RIBOSOMAL PROTEIN S6 KINASES, 90KDa the proteins in this family are sensitive to the inhibitory effects of RAPAMYCIN and contain a single kinase domain. They are referred to as 70kDa proteins, however ALTERNATIVE SPLICING of mRNAs for proteins in this class also results in 85kDa variants being formed.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.7.11.1
Previous Indexing: Ribosomal Protein S6 Kinases (1990-2002)
Public MeSH Note: 2005; see RIBOSOMAL PROTEIN S6 KINASES, 70 KD 2003-2004; for P70 S6 KINASE & P70S6K see RIBOSOMAL PROTEIN S6 KINASES 1998-2002
History Note: 2005(2003); for P70 S6 KINASE & P70S6K use RIBOSOMAL PROTEIN S6 KINASES 1998-2002
DeCS ID: 37341
Unique ID: D038762
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2003/01/01
Date of Entry: 2002/07/03
Revision Date: 2015/11/24
Ribosomal Protein S6 Kinases, 70-kDa - Preferred
Concept UI M0417009
Scope note A family of ribosomal protein S6 kinases that are considered the major physiological kinases for RIBOSOMAL PROTEIN S6. Unlike RIBOSOMAL PROTEIN S6 KINASES, 90KDa the proteins in this family are sensitive to the inhibitory effects of RAPAMYCIN and contain a single kinase domain. They are referred to as 70kDa proteins, however ALTERNATIVE SPLICING of mRNAs for proteins in this class also results in 85kDa variants being formed.
Preferred term Ribosomal Protein S6 Kinases, 70-kDa
Entry term(s) Ribosomal Protein S6 Kinases, 70 kDa
S6 Kinase, p70
p70 S6 Kinase
p70s6k



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey