| Descriptor English: | Ribosomal Protein S6 Kinases, 90-kDa | ||||||
| Descriptor Spanish: |
Proteínas Quinasas S6 Ribosómicas 90-kDa
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| Descriptor Portuguese: | Proteínas Quinases S6 Ribossômicas 90-kDa | ||||||
| Descriptor French: | Ribosomal Protein S6 Kinases, 90-kDa | ||||||
| Entry term(s): |
MAP Kinase Activated Kinase 1 MAP Kinase Activated Protein Kinase 1 MAP-Kinase-Activated Kinase 1 MAP-Kinase-Activated Protein Kinase 1 MAPKAP Kinase 1 MAPKAP Kinase-1 MAPKAP-K1 MAPKAPK1 Ribosomal Protein S6 Kinase, 90 kDa Ribosomal Protein S6 Kinase, 90-kDa Ribosomal Protein S6 Kinases, 90 kDa p90 Ribosomal S6 Kinase p90(rsk) pp90(rsk) |
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| Tree number(s): |
D08.811.913.696.620.682.700.862.500 D12.776.476.563.862.500 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D038744 | ||||||
| Scope note: | A family of ribosomal protein S6 kinases that are structurally distinguished from RIBOSOMAL PROTEIN S6 KINASES, 70-KDA by their apparent molecular size and the fact they contain two functional kinase domains. Although considered RIBOSOMAL PROTEIN S6 KINASES, members of this family are activated via the MAP KINASE SIGNALING SYSTEM and have been shown to act on a diverse array of substrates that are involved in cellular regulation such as RIBOSOMAL PROTEIN S6 and CAMP RESPONSE ELEMENT-BINDING PROTEIN. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 2.7.11.1 | ||||||
| Previous Indexing: |
Protein-Serine-Threonine Kinases (1993-1997) Ribosomal Protein S6 Kinase (1998-2002) |
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| Public MeSH Note: | 2005; see RIBOSOMAL PROTEIN S6 KINASES, 90KD 2003-2004; MAP-KINASE-ACTIVATED KINASE 1 (now RIBOSOMAL PROTEIN S6 KINASES, 90KDa) was indexed under RIBOSOMAL PROTEIN S6 KINASE 1993-2002; for PP90(RSK) & PP90(RSK) see RIBOSOMAL PROTEIN S6 KINASE 1998-2002 |
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| History Note: | 2005(2002); for PP90(RSK) & PP90(RSK) use RIBOSOMAL PROTEIN S6 KINASES 1998-2002 |
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| DeCS ID: | 37342 | ||||||
| Unique ID: | D038744 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2003/01/01 | ||||||
| Date of Entry: | 2002/07/03 | ||||||
| Revision Date: | 2015/11/24 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Ribosomal Protein S6 Kinases, 90-kDa
- Preferred
| Concept UI |
M0223389 |
| Scope note | A family of ribosomal protein S6 kinases that are structurally distinguished from RIBOSOMAL PROTEIN S6 KINASES, 70-KDA by their apparent molecular size and the fact they contain two functional kinase domains. Although considered RIBOSOMAL PROTEIN S6 KINASES, members of this family are activated via the MAP KINASE SIGNALING SYSTEM and have been shown to act on a diverse array of substrates that are involved in cellular regulation such as RIBOSOMAL PROTEIN S6 and CAMP RESPONSE ELEMENT-BINDING PROTEIN. |
| Preferred term | Ribosomal Protein S6 Kinases, 90-kDa |
| Entry term(s) |
MAP Kinase Activated Kinase 1 MAP Kinase Activated Protein Kinase 1 MAP-Kinase-Activated Kinase 1 MAP-Kinase-Activated Protein Kinase 1 MAPKAP Kinase 1 MAPKAP Kinase-1 MAPKAP-K1 MAPKAPK1 Ribosomal Protein S6 Kinase, 90 kDa Ribosomal Protein S6 Kinase, 90-kDa Ribosomal Protein S6 Kinases, 90 kDa p90 Ribosomal S6 Kinase p90(rsk) pp90(rsk) |
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