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Descriptor English: Calgranulin A
Descriptor Spanish: Calgranulina A
Descriptor calgranulina A
Scope note: Miembro de 10,8 kDa de la familia de proteínas de unión al calcio S-100, que puede formar homo o heterocomplejos con la CALGRANULINA B y una variedad de otras proteínas. El heterodímero calgranulina A/B se conoce con la denominación de COMPLEJO DE ANTÍGENO L1 LEUCOCITARIO. La calgranulina A se encuentra en muchos tipos celulares, como GRANULOCITOS, QUERATINOCITOS y mielomonocitos y se ha demostrado que actúa como sustancia quimiotáctica para los NEUTRÓFILOS. Por estar presente en la inflamación aguda y ausente en la inflamación crónica, es un marcador biológico útil de numerosos procesos patológicos.
Descriptor Portuguese: Calgranulina A
Descriptor French: Calgranuline A
Entry term(s): 60B8 B Antigen
60B8-B Antigen
A8 Protein, S100
Antigen, 60B8-B
Antigen, Cystic Fibrosis
CABP-P8
Cystic Fibrosis Antigen
Leukocyte L1 Protein Light Chain
MRP 8 Protein
MRP-8 Protein
MRP8 Protein
Macrophage Related Protein 8
Macrophage-Related Protein-8
Myeloid Calcium Binding Protein P8
Myeloid Calcium-Binding Protein P8
S100 A8 Protein
S100A8 Protein
Tree number(s): D12.776.157.125.750.500.100
D12.776.631.658.750.500
D23.050.301.562.100
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D040501
Scope note: A 10.8-kDa member of the S-100 family of calcium-binding proteins that can form homo- or heterocomplexes with CALGRANULIN B and a variety of other proteins. The calgranulin A/B heterodimer is known as LEUKOCYTE L1 ANTIGEN COMPLEX. Calgranulin A is found in many cell types including GRANULOCYTES; KERATINOCYTES; and myelomonocytes, and has been shown to act as a chemotactic substance for NEUTROPHILS. Because it is present in acute inflammation but absent in chronic inflammation, it is a useful biological marker for a number of pathological conditions.
Allowable Qualifiers: AD administration & dosage
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CH chemistry
CL classification
DE drug effects
DF deficiency
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PH physiology
RE radiation effects
TU therapeutic use
UL ultrastructure
Previous Indexing: Antigens, Differentiation (1989-2002)
Calcium-Binding Proteins (1989-2002)
Public MeSH Note: 2003; CALGRANULIN A was indexed under CALCIUM-BINDING BINDING PROTEINS 1989-2002; MRP-8 PROTEIN (now CALGRANULIN A) was indexed under ANTIGENS, DIFFERENTIATION & CALCIUM-BINDING PROTEINS 1989-2002
History Note: 2003; use CALGRANULIN A (NM) 1998-2002;
DeCS ID: 37388
Unique ID: D040501
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2003/01/01
Date of Entry: 2002/07/02
Revision Date: 2016/01/07
Calgranulin A - Preferred
Concept UI M0169795
Scope note A 10.8-kDa member of the S-100 family of calcium-binding proteins that can form homo- or heterocomplexes with CALGRANULIN B and a variety of other proteins. The calgranulin A/B heterodimer is known as LEUKOCYTE L1 ANTIGEN COMPLEX. Calgranulin A is found in many cell types including GRANULOCYTES; KERATINOCYTES; and myelomonocytes, and has been shown to act as a chemotactic substance for NEUTROPHILS. Because it is present in acute inflammation but absent in chronic inflammation, it is a useful biological marker for a number of pathological conditions.
Preferred term Calgranulin A
Entry term(s) 60B8 B Antigen
60B8-B Antigen
A8 Protein, S100
Antigen, 60B8-B
Antigen, Cystic Fibrosis
CABP-P8
Cystic Fibrosis Antigen
Leukocyte L1 Protein Light Chain
MRP 8 Protein
MRP-8 Protein
MRP8 Protein
Macrophage Related Protein 8
Macrophage-Related Protein-8
Myeloid Calcium Binding Protein P8
Myeloid Calcium-Binding Protein P8
S100 A8 Protein
S100A8 Protein



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