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Descriptor English: S100 Proteins
Descriptor Spanish: Proteínas S100
Descriptor proteínas S100
Entry term(s) antígeno S 100
familia de proteínas S100
proteína S 100 del tejido nervioso
proteína S100
Scope note: Familia de proteínas muy ácidas fijadoras de calcio que se encuentran en gran concentración en el cerebro. Se cree que se originan en la glia. Se encuentran también en otros órganos del organismo. Tienen en común el motivo mano-EF (MOTIVOS MANO-EF) que se encuentran en numerosas proteínas fijadoras de calcio. El nombre de esta familia deriva de la propiedad de ser solubles en solución de sulfato amónico saturado al 100 por ciento.
Descriptor Portuguese: Proteínas S100
Descriptor French: Protéines S100
Entry term(s): Antigen S 100
Nerve Tissue Protein S 100
Protein, S100
S 100 Protein
S-100 Protein
S100 Protein
S100 Protein Family
Tree number(s): D12.776.157.125.750
D12.776.631.655
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D009418
Scope note: A family of highly acidic calcium-binding proteins found in large concentration in the brain and believed to be glial in origin. They are also found in other organs in the body. They have in common the EF-hand motif (EF HAND MOTIFS) found on a number of calcium binding proteins. The name of this family derives from the property of being soluble in a 100% saturated ammonium sulfate solution.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Nerve Tissue Proteins (1966-1972)
Public MeSH Note: 2003; see NERVE TISSUE PROTEIN S 100 1984-2002, see NERVE TISSUE PROTEINS 1975-1983
History Note: 2003(1973)
DeCS ID: 24250
Unique ID: D009418
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1984/01/01
Date of Entry: 1999/01/01
Revision Date: 2020/05/27
S100 Proteins - Preferred
Concept UI M0014662
Scope note A family of highly acidic calcium-binding proteins found in large concentration in the brain and believed to be glial in origin. They are also found in other organs in the body. They have in common the EF-hand motif (EF HAND MOTIFS) found on a number of calcium binding proteins. The name of this family derives from the property of being soluble in a 100% saturated ammonium sulfate solution.
Preferred term S100 Proteins
Entry term(s) Antigen S 100
Nerve Tissue Protein S 100
Protein, S100
S 100 Protein
S-100 Protein
S100 Protein
S100 Protein Family



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