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Descriptor English: | MicroRNAs | ||||||
Descriptor Spanish: |
MicroARNs
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Descriptor Portuguese: | MicroRNAs | ||||||
Descriptor French: | microARN | ||||||
Entry term(s): |
Petit ARN temporaire miARN miARN primaire micro-ARN microARN primaire pri-miARN pré-miARN |
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Tree number(s): |
D13.150.650.319 D13.444.735.150.319 D13.444.735.790.552.500 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D035683 | ||||||
Scope note: | Small double-stranded, non-protein coding RNAs, 21-25 nucleotides in length generated from single-stranded microRNA gene transcripts by the same RIBONUCLEASE III, Dicer, that produces small interfering RNAs (RNA, SMALL INTERFERING). They become part of the RNA-INDUCED SILENCING COMPLEX and repress the translation (TRANSLATION, GENETIC) of target RNA by binding to homologous 3'UTR region as an imperfect match. The small temporal RNAs (stRNAs), let-7 and lin-4, from C. elegans, are the first 2 miRNAs discovered, and are from a class of miRNAs involved in developmental timing. |
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Allowable Qualifiers: |
AD administration et posologie AE effets indésirables AG agonistes AI antagonistes et inhibiteurs AN analyse BI biosynthèse BL sang CF liquide cérébrospinal CH composition chimique CL classification CS synthèse chimique DE effets des médicaments et des substances chimiques EC économie GE génétique HI histoire IM immunologie IP isolement et purification ME métabolisme PD pharmacologie PH physiologie PK pharmacocinétique PO intoxication RE effets des radiations SD ressources et distribution ST normes TO toxicité TU usage thérapeutique UL ultrastructure UR urine |
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Related: |
Petit ARN interférent
MeSH | ||||||
DeCS ID: | 37535 | ||||||
Unique ID: | D035683 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 2003/01/01 | ||||||
Date of Entry: | 2002/07/03 | ||||||
Revision Date: | 2013/07/09 |
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PRODUITS CHIMIQUES ET PHARMACEUTIQUES
Acides nucléiques, nucléotides et nucléosides [D13]Acides nucléiques, nucléotides et nucléosides -
PRODUITS CHIMIQUES ET PHARMACEUTIQUES
Acides nucléiques, nucléotides et nucléosides [D13]Acides nucléiques, nucléotides et nucléosides -
PRODUITS CHIMIQUES ET PHARMACEUTIQUES
Acides nucléiques, nucléotides et nucléosides [D13]Acides nucléiques, nucléotides et nucléosides
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microARN
- Preferred
microARN primaire
- Narrower
Petit ARN temporaire
- Narrower
pré-miARN
- Narrower
Concept UI |
M0407989 |
Preferred term | microARN |
Entry term(s) |
miARN micro-ARN |
Concept UI |
M0507098 |
Preferred term | microARN primaire |
Entry term(s) |
miARN primaire pri-miARN |
Concept UI |
M0408369 |
Preferred term | Petit ARN temporaire |
Concept UI |
M0507502 |
Preferred term | pré-miARN |
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