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Descriptor in English: RNA, Antisense
Descriptor in Spanish: ARN sin Sentido
Descriptor in Portuguese: RNA Antissenso
Descriptor in French: ARN antisens
Entry term(s): Anti Sense RNA
Anti-Sense RNA
Antisense RNA
RNA, Anti-Sense
Tree number(s): D13.150.650
D13.444.600.150.760
D13.444.735.150
D27.720.470.530.600.150.760
Scope note: RNA molecules which hybridize to complementary sequences in either RNA or DNA altering the function of the latter. Endogenous antisense RNAs function as regulators of gene expression by a variety of mechanisms. Synthetic antisense RNAs are used to effect the functioning of specific genes for investigative or therapeutic purposes.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
History Note: 91
DeCS UI: 29111
Descriptor UI: D016372
Date Established: 1991/01/01
Date of Entry: 1990/05/29
Revision Date: 2011/06/24
RNA, Antisense - Preferred
Concept UI M0025050
Scope note RNA molecules which hybridize to complementary sequences in either RNA or DNA altering the function of the latter. Endogenous antisense RNAs function as regulators of gene expression by a variety of mechanisms. Synthetic antisense RNAs are used to effect the functioning of specific genes for investigative or therapeutic purposes.
Preferred term RNA, Antisense
Entry term(s) Anti Sense RNA
Anti-Sense RNA
Antisense RNA
RNA, Anti-Sense



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