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Descriptor English: Leukocyte Rolling
Descriptor Spanish: Rodamiento de Leucocito
Descriptor rodamiento leucocitario
Entry term(s) rodamiento de los leucocitos
rodamiento leucocítico
Scope note: Movimiento de LEUCOCITOS esféricos, sujetos a lo largo de la superficie endotelial de la microvasculatura. La sujeción y el rodamiento implican la interacción con las SELECTINAS y otras moléculas de adhesión tanto en el ENDOTELIO como en el leucocito. Entonces los leucocitos sometidos a rodamiento son activados por las QUIMIOCINAS, se enderezan y se adhieren firmemente a la superficie endotelial, como preparación para la transmigración a través de la unión celular interendotelial. (Abbas, Cellular and Molecular Immunology, 3rd ed)
Descriptor Portuguese: Migração e Rolagem de Leucócitos
Descriptor French: Roulement des leucocytes
Entry term(s): Leucocyte Rolling
Rolling, Leucocyte
Rolling, Leukocyte
Tree number(s): G04.198.424.233.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D036904
Scope note: Movement of tethered, spherical LEUKOCYTES along the endothelial surface of the microvasculature. The tethering and rolling involves interaction with SELECTINS and other adhesion molecules in both the ENDOTHELIUM and leukocyte. The rolling leukocyte then becomes activated by CHEMOKINES, flattens out, and firmly adheres to the endothelial surface in preparation for transmigration through the interendothelial cell junction. (From Abbas, Cellular and Molecular Immunology, 3rd ed)
Allowable Qualifiers: DE drug effects
ES ethics
GE genetics
IM immunology
PH physiology
RE radiation effects
Previous Indexing: Cell Adhesion (1991-2002)
Cell Movement (1991-2002)
Public MeSH Note: 2003
History Note: 2003
DeCS ID: 37639
Unique ID: D036904
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2003/01/01
Date of Entry: 2002/07/03
Revision Date: 2016/06/23
Leukocyte Rolling - Preferred
Concept UI M0411381
Scope note Movement of tethered, spherical LEUKOCYTES along the endothelial surface of the microvasculature. The tethering and rolling involves interaction with SELECTINS and other adhesion molecules in both the ENDOTHELIUM and leukocyte. The rolling leukocyte then becomes activated by CHEMOKINES, flattens out, and firmly adheres to the endothelial surface in preparation for transmigration through the interendothelial cell junction. (From Abbas, Cellular and Molecular Immunology, 3rd ed)
Preferred term Leukocyte Rolling
Entry term(s) Leucocyte Rolling
Rolling, Leucocyte
Rolling, Leukocyte



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