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Descriptor English: RNA 5' Terminal Oligopyrimidine Sequence
Descriptor Spanish: Secuencia de Oligopirimidina en la Región 5' Terminal del ARN
Descriptor secuencia de oligopirimidinas en la región terminal 5' del ARN
Entry term(s) secuencia de oligopirimidina en la región terminal 5' del ARN
Scope note: Secuencia reguladora que se encuentra en las regiones terminales 5' del ARN. La secuencia comienza con una CITIDINA, a la que sigue una extensión de 5 a 15 NUCLEÓTIDOS DE PIRIMIDINA. El ARN mensajero que contiene el tramo terminal 5' de oligopirimidina se conoce a menudo como ARNm 5' TOP. La secuencia actúa como regulador de traducción y se ha encontrado en los ARNm para los FACTORES DE ELONGACIÓN DE PÉPTIDOS y PROTEÍNAS RIBOSÓMICAS.
Descriptor Portuguese: Sequência de Oligopirimidina na Região 5' Terminal do RNA
Descriptor French: Séquence d'oligopyrimidines en région 5' terminale d'ARN
Entry term(s): 5' TOP Messenger RNA
5' TOP Sequence
5' TOP Sequences
5' TOP mRNA
RNA 5' Terminal Oligopyrimidine Regulatory Sequence
Sequence, 5' TOP
Sequences, 5' TOP
Tree number(s): G02.111.570.080.689.687.275
G05.360.080.689.687.275
G05.360.340.024.340.137.785
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D038641
Scope note: A regulatory sequence found in the 5' terminal regions of a variety of RNA species. The sequence starts with a CYTIDINE, which is followed by a stretch of 5 to 15 PYRIMIDINE NUCLEOTIDES. Messenger RNA that contains the 5' Terminal Oligo Pyrimidine tract is often referred to as 5' TOP mRNA. The sequence acts as a translational regulator and has been found in mRNAs for PEPTIDE ELONGATION FACTORS and RIBOSOMAL PROTEINS.
Allowable Qualifiers: DE drug effects
ES ethics
GE genetics
IM immunology
PH physiology
RE radiation effects
Public MeSH Note: 2003
History Note: 2003
Entry Version: RNA 5 TERMINAL OLIGOPYRIMIDINE SEQ
DeCS ID: 37649
Unique ID: D038641
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2003/01/01
Date of Entry: 2002/07/03
Revision Date: 2013/07/09
RNA 5' Terminal Oligopyrimidine Sequence - Preferred
Concept UI M0416549
Scope note A regulatory sequence found in the 5' terminal regions of a variety of RNA species. The sequence starts with a CYTIDINE, which is followed by a stretch of 5 to 15 PYRIMIDINE NUCLEOTIDES. Messenger RNA that contains the 5' Terminal Oligo Pyrimidine tract is often referred to as 5' TOP mRNA. The sequence acts as a translational regulator and has been found in mRNAs for PEPTIDE ELONGATION FACTORS and RIBOSOMAL PROTEINS.
Preferred term RNA 5' Terminal Oligopyrimidine Sequence
Entry term(s) 5' TOP Sequence
5' TOP Sequences
RNA 5' Terminal Oligopyrimidine Regulatory Sequence
Sequence, 5' TOP
Sequences, 5' TOP
5' TOP mRNA - Related but not broader or narrower
Concept UI M0416550
Preferred term 5' TOP mRNA
Entry term(s) 5' TOP Messenger RNA



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