| Descriptor English: | Long-Term Synaptic Depression | ||||||
| Descriptor Spanish: |
Depresión Sináptica a Largo Plazo
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| Descriptor Portuguese: | Depressão Sináptica de Longo Prazo | ||||||
| Descriptor French: | Dépression synaptique à long terme | ||||||
| Entry term(s): |
Depotentiation Depression, Homosynaptic Depression, Neurophysiological Long-Term Depression, Physiological Long-Term Depressions, Neurophysiological Long-Term Depressions, Physiological Long-Term Homosynaptic Depression Long Term Depression, Neurophysiologic Long Term Depression, Neurophysiological Long Term Depression, Physiologic Long Term Depression, Physiological Long Term Synaptic Depression Long-Term Depression, Neurophysiologic Long-Term Depression, Neurophysiological Long-Term Depression, Physiologic Long-Term Depression, Physiological Long-Term Depressions, Neurophysiological Long-Term Depressions, Physiological Neurophysiologic Long-Term Depression Neurophysiological Long-Term Depression Neurophysiological Long-Term Depressions Physiologic Long-Term Depression Physiological Long-Term Depression Physiological Long-Term Depressions Synaptic Depression, Long-Term |
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| Tree number(s): |
G11.561.638.355 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D036881 | ||||||
| Scope note: | A persistent activity-dependent decrease in synaptic efficacy between NEURONS. It typically occurs following repeated low-frequency afferent stimulation, but it can be induced by other methods. Long-term depression appears to play a role in MEMORY. |
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| Annotation: | note category: do not confuse with clinical DEPRESSION or DEPRESSIVE DISORDERS |
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| Allowable Qualifiers: |
DE drug effects ES ethics GE genetics IM immunology PH physiology RE radiation effects |
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| Previous Indexing: |
Neuronal Plasticity (1985-2002) |
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| Public MeSH Note: | 2008; see LONG-TERM DEPRESSION (PHYSIOLOGY) 2003-2007 |
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| History Note: | 2008 (2003) |
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| DeCS ID: | 37661 | ||||||
| Unique ID: | D036881 | ||||||
| NLM Classification: | WL 102 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2003/01/01 | ||||||
| Date of Entry: | 2002/07/03 | ||||||
| Revision Date: | 2016/06/23 |
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Long-Term Synaptic Depression
- Preferred
Depotentiation
- Related but not broader or narrower
| Concept UI |
M0411349 |
| Scope note | A persistent activity-dependent decrease in synaptic efficacy between NEURONS. It typically occurs following repeated low-frequency afferent stimulation, but it can be induced by other methods. Long-term depression appears to play a role in MEMORY. |
| Preferred term | Long-Term Synaptic Depression |
| Entry term(s) |
Depression, Neurophysiological Long-Term Depression, Physiological Long-Term Depressions, Neurophysiological Long-Term Depressions, Physiological Long-Term Long Term Depression, Neurophysiologic Long Term Depression, Neurophysiological Long Term Depression, Physiologic Long Term Depression, Physiological Long Term Synaptic Depression Long-Term Depression, Neurophysiologic Long-Term Depression, Neurophysiological Long-Term Depression, Physiologic Long-Term Depression, Physiological Long-Term Depressions, Neurophysiological Long-Term Depressions, Physiological Neurophysiologic Long-Term Depression Neurophysiological Long-Term Depression Neurophysiological Long-Term Depressions Physiologic Long-Term Depression Physiological Long-Term Depression Physiological Long-Term Depressions Synaptic Depression, Long-Term |
| Concept UI |
M0411350 |
| Scope note | Long-term depression resulting from repeated low-frequency stimulation in only the pathway receiving the induction protocol. It follows induction of LONG-TERM POTENTIATION and reverses it. |
| Preferred term | Depotentiation |
| Entry term(s) |
Depression, Homosynaptic Homosynaptic Depression |
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