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Descriptor English: Metalloproteases
Descriptor Spanish: Metaloproteasas
Descriptor Portuguese: Metaloproteases
Descriptor French: Metalloproteases
Entry term(s): Metallopeptidase
Metallopeptidases
Metalloprotease
Metalloproteinase
Metalloproteinases
Tree number(s): D08.811.277.656.675
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D045726
Scope note: Proteases which use a metal, normally ZINC, in the catalytic mechanism. This group of enzymes is inactivated by metal CHELATORS.
Annotation: general or unspecified; prefer specifics
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.4.-
Previous Indexing: Metalloendopeptidases (1987-2003)
Public MeSH Note: 2004; see METALLOENDOPEPTIDASES 1988-2003
History Note: 2004; use METALLOENDOPEPTIDASES 1988-2003
DeCS ID: 38178
Unique ID: D045726
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 2020/05/27
Metalloproteases - Preferred
Concept UI M0449114
Scope note Proteases which use a metal, normally ZINC, in the catalytic mechanism. This group of enzymes is inactivated by metal CHELATORS.
Preferred term Metalloproteases
Entry term(s) Metallopeptidase
Metallopeptidases
Metalloprotease
Metalloproteinase
Metalloproteinases



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