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Descriptor English: Cathepsins
Descriptor Spanish: Catepsinas
Descriptor catepsinas
Scope note: Grupo de proteinasas lisosómicas o endopeptidasas que se encuentran en los extractos acuosos de diversos tejidos animales. Funcionan óptimamente en pH ácido. Las catepsinas se presentan como una variedad de subtipos enzimáticos, incluidas las SERINA PROTEASAS, ASPÁRTICO PROTEINASAS y CISTEÍNA PROTEASAS.
Descriptor Portuguese: Catepsinas
Descriptor French: Cathepsines
Entry term(s): Cathepsin
Tree number(s): D08.811.277.656.224
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D002403
Scope note: A group of lysosomal proteinases or endopeptidases found in aqueous extracts of a variety of animal tissues. They function optimally within an acidic pH range. The cathepsins occur as a variety of enzyme subtypes including SERINE PROTEASES; ASPARTIC PROTEINASES; and CYSTEINE PROTEASES.
Annotation: note specifics
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.4.-
Public MeSH Note: 79; was CATHEPSIN 1965-78
Online Note: use CATHEPSINS to search CATHEPSIN 1966-78
History Note: 79; was CATHEPSIN 1963-78 (Prov 1963-64)
DeCS ID: 2445
Unique ID: D002403
NLM Classification: QU 136
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1965/01/01
Date of Entry: 1999/01/01
Revision Date: 2009/07/06
Cathepsins - Preferred
Concept UI M0003661
Scope note A group of lysosomal proteinases or endopeptidases found in aqueous extracts of a variety of animal tissues. They function optimally within an acidic pH range. The cathepsins occur as a variety of enzyme subtypes including SERINE PROTEASES; ASPARTIC PROTEINASES; and CYSTEINE PROTEASES.
Preferred term Cathepsins
Entry term(s) Cathepsin



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