| Descriptor English: | Receptor, TIE-2 | ||||||
| Descriptor Spanish: |
Receptor TIE-2
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| Descriptor Portuguese: | Receptor TIE-2 | ||||||
| Descriptor French: | Récepteur TIE-2 | ||||||
| Entry term(s): |
Angiopoietin Receptor Tie 2 Angiopoietin Receptor Tie-2 Receptor Tie-2, Angiopoietin Receptor, TIE 2 Receptor, Tek Receptor, Tie2 TIE 2 Receptor Tyrosine Kinase TIE-2 Receptor TIE-2 Receptor Tyrosine Kinase TIE-2-RTK TIE2 Tyrosine Kinase Tek Receptor Tie-2, Angiopoietin Receptor Tie2 Receptor Tyrosine Kinase, TIE2 |
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| Tree number(s): |
D08.811.913.696.620.682.725.400.925.500 D12.776.476.568.400.925.500 D12.776.543.750.630.687.500 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D042787 | ||||||
| Scope note: | A TIE receptor tyrosine kinase that is found almost exclusively on ENDOTHELIAL CELLS. It is required for both normal embryonic vascular development (NEOVASCULARIZATION, PHYSIOLOGIC) and tumor angiogenesis (NEOVASCULARIZATION, PATHOLOGIC). |
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| Annotation: | see SCR for organism-specific terms |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 2.7.10.1 | ||||||
| Previous Indexing: |
Protein-Tyrosine Kinase (1993) Receptor Protein-Tyrosine Kinases (1994-2003) |
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| Public MeSH Note: | 2004; TIE-2 RECEPTOR TYROSINE KINASE (now RECEPTOR TIE-2) was indexed under RECEPTOR PROTEIN-TYROSINE KINASES 1994-2004 & under PROTEIN-TYROSINE KINASE 1993 |
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| History Note: | 2004; use RECEPTOR TIE-2 (NM) 1993-2003 |
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| Entry Version: | RECEPT TIE 2 |
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| DeCS ID: | 38229 | ||||||
| Unique ID: | D042787 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2004/01/01 | ||||||
| Date of Entry: | 2003/07/09 | ||||||
| Revision Date: | 2016/05/31 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Receptor, TIE-2
- Preferred
| Concept UI |
M0217220 |
| Scope note | A TIE receptor tyrosine kinase that is found almost exclusively on ENDOTHELIAL CELLS. It is required for both normal embryonic vascular development (NEOVASCULARIZATION, PHYSIOLOGIC) and tumor angiogenesis (NEOVASCULARIZATION, PATHOLOGIC). |
| Preferred term | Receptor, TIE-2 |
| Entry term(s) |
Angiopoietin Receptor Tie 2 Angiopoietin Receptor Tie-2 Receptor Tie-2, Angiopoietin Receptor, TIE 2 Receptor, Tek Receptor, Tie2 TIE 2 Receptor Tyrosine Kinase TIE-2 Receptor TIE-2 Receptor Tyrosine Kinase TIE-2-RTK TIE2 Tyrosine Kinase Tek Receptor Tie-2, Angiopoietin Receptor Tie2 Receptor Tyrosine Kinase, TIE2 |
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