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Descriptor English: Receptors, TIE
Descriptor Spanish: Receptores TIE
Descriptor receptores TIE
Entry term(s) familia de receptores TIE
receptor TIE
receptor TIE de tirosina-cinasas
receptor tirosina-cinasa TIE
receptores tirosina-cinasas TIE
Scope note: Familia de receptores tirosina cinasa estructuralmente relacionados, que se expresan predominantemente en las CÉLULAS ENDOTELIALES y son esenciales para el desarrollo de los VASOS SANGUÍNEOS (NEOVASCULARIZACIÓN FISIOLÓGICA). El nombre deriva del hecho de que son tirosina cinasas que contienen dominios Ig y EGF.
Descriptor Portuguese: Receptores de TIE
Descriptor French: Récepteurs TIE
Entry term(s): Family, TIE Receptor
Receptor Family, TIE
Receptor Tyrosine Kinase TIE
TIE Receptor
TIE Receptor Family
TIE Receptor Tyrosine Kinase
TIE Receptor Tyrosine Kinases
TIE Receptors
Tree number(s): D08.811.913.696.620.682.725.400.925
D12.776.476.568.400.925
D12.776.543.750.630.687
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D042764
Scope note: A family of structurally-related tyrosine kinase receptors that are expressed predominantly in ENDOTHELIAL CELLS and are essential for development of BLOOD VESSELS (NEOVASCULARIZATION, PHYSIOLOGIC). The name derives from the fact that they are tyrosine kinases that contain Ig and EGF domains.
Annotation: general or unspecified; prefer specifics
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.7.10.1
Previous Indexing: Receptor Protein-Tyrosine Kinases (1994-2003)
Receptors, Cell Surface (1992-1993)
Public MeSH Note: 2004; TIE RECEPTOR TYROSINE KINASES (now RECEPTORS, TIE) was indexed under RECEPTOR PROTEIN-TYROSINE KINASES 1994-2003; under RECEPTORS, CELL SURFACE & PROTEIN-TYROSINE KINASE 1992-1993
History Note: 2004; use RECEPTORS, TIE (NM) 1999-2003
Entry Version: RECEPT TIE
DeCS ID: 38227
Unique ID: D042764
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 2016/05/31
Receptors, TIE - Preferred
Concept UI M0209740
Scope note A family of structurally-related tyrosine kinase receptors that are expressed predominantly in ENDOTHELIAL CELLS and are essential for development of BLOOD VESSELS (NEOVASCULARIZATION, PHYSIOLOGIC). The name derives from the fact that they are tyrosine kinases that contain Ig and EGF domains.
Preferred term Receptors, TIE
Entry term(s) Family, TIE Receptor
Receptor Family, TIE
Receptor Tyrosine Kinase TIE
TIE Receptor
TIE Receptor Family
TIE Receptor Tyrosine Kinase
TIE Receptor Tyrosine Kinases
TIE Receptors



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