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Descriptor English: Angiopoietin-1
Descriptor Spanish: Angiopoyetina 1
Descriptor angiopoyetina 1
Scope note: El primer miembro que se descubrió de la familia de las angiopoyetinas. Puede desempeñar un papel en el aumento de brotes y ramificaciones de los VASOS SANGUÍNEOS. La angiopoyetina 1 se une específicamente al RECEPTOR TIE-2 y lo estimula. Existen varias isoformas de angiopoyetina 1 debidas al AYUSTE ALTERNATIVO de sus ARNm.
Descriptor Portuguese: Angiopoietina-1
Descriptor French: Angiopoïétine-1
Entry term(s): Angiopoietin 1
Tree number(s): D12.644.276.100.100.100
D12.776.467.100.100.100
D23.529.100.100.100
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D042683
Scope note: The first to be discovered member of the angiopoietin family. It may play a role in increasing the sprouting and branching of BLOOD VESSELS. Angiopoietin-1 specifically binds to and stimulates the TIE-2 RECEPTOR. Several isoforms of angiopoietin-1 occur due to ALTERNATIVE SPLICING of its mRNA.
Annotation: see SCR for organism-specific terms
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Previous Indexing: Angiogenesis Factor (2003)
Membrane Glycoproteins (1997-2003)
Public MeSH Note: 2004; ANGIOPOIETIN-1 was indexed under MEMBRANE GLYCOPROTEINS 1997-2003 & ANGIOGENESIS FACTOR 2003
History Note: 2004; use ANGIOPOIETIN-1 (NM) 1997-2003
DeCS ID: 38238
Unique ID: D042683
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 2006/07/05
Angiopoietin-1 - Preferred
Concept UI M0270236
Scope note The first to be discovered member of the angiopoietin family. It may play a role in increasing the sprouting and branching of BLOOD VESSELS. Angiopoietin-1 specifically binds to and stimulates the TIE-2 RECEPTOR. Several isoforms of angiopoietin-1 occur due to ALTERNATIVE SPLICING of its mRNA.
Preferred term Angiopoietin-1
Entry term(s) Angiopoietin 1



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