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Descriptor English: beta-Transducin Repeat-Containing Proteins
Descriptor Spanish: Proteínas con Repetición de beta-Transducina
Descriptor proteínas con beta-transducina de repetición
Entry term(s) proteínas que contienen beta-transducina de repetición
Scope note: Familia de proteínas con dominio F-box que contienen secuencias homólogas a las subunidades beta de la transducina(BETA-TRANSDUCINA). Estas proteínas juegan un importante papel en la vía de degradación proteica, al convertirse en componenetes de las PROTEÍNA-LIGASAS SKP-CULLINA-F-BOX, las cuales actúan selectivamente sobre un subgrupo de proteínas entre las que se incluyen la beta-catenina y la IkappaBbeta.
Descriptor Portuguese: Proteínas Contendo Repetições de beta-Transducina
Descriptor French: Protéines à répétitions de séquences bêta-transducine
Entry term(s): Protein, beta-Transducin Repeat-Containing
Repeat-Containing Protein, beta-Transducin
Repeat-Containing Proteins, beta-Transducin
beta TrCP
beta Transducin Repeat Containing Protein
beta Transducin Repeat Containing Proteins
beta-TrCP
beta-Transducin Repeat-Containing Protein
betaTrCP
Tree number(s): D12.776.157.169.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D044844
Scope note: A family of F-box domain proteins that contain sequences that are homologous to the beta subunit of transducin (BETA-TRANSDUCIN). They play an important role in the protein degradation pathway by becoming components of SKP CULLIN F-BOX PROTEIN LIGASES, which selectively act on a subset of proteins including beta-catenin and IkappaBbeta.
Annotation: see SCR for organism specific terms
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2004
History Note: 2004
DeCS ID: 38253
Unique ID: D044844
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 2006/07/05
beta-Transducin Repeat-Containing Proteins - Preferred
Concept UI M0219301
Scope note A family of F-box domain proteins that contain sequences that are homologous to the beta subunit of transducin (BETA-TRANSDUCIN). They play an important role in the protein degradation pathway by becoming components of SKP CULLIN F-BOX PROTEIN LIGASES, which selectively act on a subset of proteins including beta-catenin and IkappaBbeta.
Preferred term beta-Transducin Repeat-Containing Proteins
Entry term(s) Protein, beta-Transducin Repeat-Containing
Repeat-Containing Protein, beta-Transducin
Repeat-Containing Proteins, beta-Transducin
beta TrCP
beta Transducin Repeat Containing Protein
beta Transducin Repeat Containing Proteins
beta-TrCP
beta-Transducin Repeat-Containing Protein
betaTrCP



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