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Descriptor English: Receptor, PAR-1
Descriptor Spanish: Receptor PAR-1
Descriptor receptor PAR-1
Entry term(s) receptor 1 activado por proteasa
Scope note: Subtipo de receptor de trombina que se acopla a las PROTEÍNAS DE UNIÓN A GTP HETEROTRIMÉRICAS con la consiguiente activación de diversos mecanismos de señalización, como la disminución del AMP CÍCLICO intracelular, el aumento de las FOSFOLIPASAS TIPO C y el aumento de la FOSFOLIPASA A2.
Descriptor Portuguese: Receptor PAR-1
Descriptor French: Récepteur de type PAR-1
Entry term(s): PAR 1 Receptor
PAR-1 Receptor
PAR1 Receptor
Protease Activated Receptor 1
Protease-Activated Receptor 1
Proteinase Activated Receptor 1
Proteinase-Activated Receptor 1
Receptor, PAR 1
Receptor, PAR1
Tree number(s): D12.776.395.550.625.800.790
D12.776.543.550.625.800.790
D12.776.543.750.695.875.500
D12.776.543.750.705.675.892.790
D12.776.543.750.750.850.399
D12.776.543.750.792.500.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D044463
Scope note: A thrombin receptor subtype that couples to HETEROTRIMERIC GTP-BINDING PROTEINS resulting in the activation of a variety of signaling mechanisms including decreased intracellular CYCLIC AMP, increased TYPE C PHOSPHOLIPASES and increased PHOSPHOLIPASE A2.
Allowable Qualifiers: AD administration & dosage
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CH chemistry
CL classification
DE drug effects
DF deficiency
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PH physiology
RE radiation effects
TU therapeutic use
UL ultrastructure
Previous Indexing: Receptors, Thrombin (1997-2003)
Public MeSH Note: 2004; PROTEASE-ACTIVATED RECEPTOR-1 (now RECEPTOR, PROTIENASE-ACTIVATED) was indexed under RECEPTORS, THROMBIN 1997-2003
History Note: 2004; use RECEPTOR, PROTEINASE-ACTIVATED 1 (NM) 1997-2003
DeCS ID: 38257
Unique ID: D044463
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 2016/06/17
Receptor, PAR-1 - Preferred
Concept UI M0283418
Scope note A thrombin receptor subtype that couples to HETEROTRIMERIC GTP-BINDING PROTEINS resulting in the activation of a variety of signaling mechanisms including decreased intracellular CYCLIC AMP, increased TYPE C PHOSPHOLIPASES and increased PHOSPHOLIPASE A2.
Preferred term Receptor, PAR-1
Entry term(s) PAR 1 Receptor
PAR-1 Receptor
PAR1 Receptor
Protease Activated Receptor 1
Protease-Activated Receptor 1
Proteinase Activated Receptor 1
Proteinase-Activated Receptor 1
Receptor, PAR 1
Receptor, PAR1



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