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Descriptor in English: beta-Lactams
Descriptor in Spanish: beta-Lactamas
Descriptor in Portuguese: beta-Lactamas
Descriptor in French: bêta-Lactames
Entry term(s): 4-Thia-1-Azabicyclo(3.2.0)Heptanes
4-Thia-1-Azabicyclo(4.2.0)Octanes
beta Lactams
Tree number(s): D02.065.589.099
D02.886.108
D03.633.100.300
Scope note: Four-membered cyclic AMIDES, best known for the PENICILLINS based on a bicyclo-thiazolidine, as well as the CEPHALOSPORINS based on a bicyclo-thiazine, and including monocyclic MONOBACTAMS. The BETA-LACTAMASES hydrolyze the beta lactam ring, accounting for BETA-LACTAM RESISTANCE of infective bacteria.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
History Note: 2005; use LACTAMS 1996-2004
DeCS UI: 38654
Descriptor UI: D047090
Date Established: 2005/01/01
Date of Entry: 2004/07/07
Revision Date: 2016/05/31
beta-Lactams - Preferred
Concept UI M0012144
Scope note Four-membered cyclic AMIDES, best known for the PENICILLINS based on a bicyclo-thiazolidine, as well as the CEPHALOSPORINS based on a bicyclo-thiazine, and including monocyclic MONOBACTAMS. The BETA-LACTAMASES hydrolyze the beta lactam ring, accounting for BETA-LACTAM RESISTANCE of infective bacteria.
Preferred term beta-Lactams
Entry term(s) beta Lactams
4-Thia-1-Azabicyclo(4.2.0)Octanes - Related but not broader or narrower
Concept UI M0499753
Preferred term 4-Thia-1-Azabicyclo(4.2.0)Octanes
4-Thia-1-Azabicyclo(3.2.0)Heptanes - Related but not broader or narrower
Concept UI M0499752
Preferred term 4-Thia-1-Azabicyclo(3.2.0)Heptanes



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