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Descriptor English: Mitogen-Activated Protein Kinase 6
Descriptor Spanish: Proteína Quinasa 6 Activada por Mitógenos
Descriptor proteína cinasa activada por mitógenos 6
Entry term(s) cinasa 3 regulada por señales extracelulares
proteína cinasa 6 activada por mitógenos
proteína quinasa 6 activada por mitógenos
proteína quinasa activada por mitógenos 6
Scope note: MAP quinasa de 97 kDa regulada por señales extracelulares. Las concentraciones de proteína quinasa activada por mitógenos 6 se elevan durante la diferenciación celular, en tanto que en las células en proliferación la enzima es degradada rápidamente por medio del COMPLEJO ENDOPEPTIDASA DEL PROTEASOMA.
Descriptor Portuguese: Proteína Quinase 6 Ativada por Mitógeno
Descriptor French: Mitogen-Activated Protein Kinase 6
Entry term(s): ERK3 Kinase
Extracellular Signal Regulated Kinase 3
Extracellular Signal-Regulated Kinase 3
Kinase, ERK3
MAPK6 Mitogen Activated Protein Kinase
MAPK6 Mitogen-Activated Protein Kinase
Mitogen Activated Protein Kinase 6
p97(MAPK) Protein
p97MAPK Protein
Tree number(s): D08.811.913.696.620.682.700.567.249.875
D12.776.476.563.567.249.875
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D048053
Scope note: A 97-kDa extracellular signal-regulated MAP kinase. Mitogen-activated protein kinase 6 levels increase during cellular differentiation, while in proliferating cells the enzyme is degraded rapidly via the PROTEASOME ENDOPEPTIDASE COMPLEX.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.7.11.24
Previous Indexing: Mitogen-Activated Protein Kinases (1991-2004)
Public MeSH Note: 2005; MITOGEN-ACTIVATED PROTEIN KINASE 6 was indexed under MITOGEN-ACTIVATED PROTEIN KINASES 2000-2004, under CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE 1994-2000 & under PROTEIN KINASES 1991-1993
History Note: 2005(1991)
DeCS ID: 38729
Unique ID: D048053
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2005/01/01
Date of Entry: 2004/07/07
Revision Date: 2015/11/24
Mitogen-Activated Protein Kinase 6 - Preferred
Concept UI M0188319
Scope note A 97-kDa extracellular signal-regulated MAP kinase. Mitogen-activated protein kinase 6 levels increase during cellular differentiation, while in proliferating cells the enzyme is degraded rapidly via the PROTEASOME ENDOPEPTIDASE COMPLEX.
Preferred term Mitogen-Activated Protein Kinase 6
Entry term(s) ERK3 Kinase
Extracellular Signal Regulated Kinase 3
Extracellular Signal-Regulated Kinase 3
Kinase, ERK3
MAPK6 Mitogen Activated Protein Kinase
MAPK6 Mitogen-Activated Protein Kinase
Mitogen Activated Protein Kinase 6
p97(MAPK) Protein
p97MAPK Protein



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