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Descriptor English: Mitogen-Activated Protein Kinases
Descriptor Spanish: Proteínas Quinasas Activadas por Mitógenos
Descriptor Portuguese: Proteínas Quinases Ativadas por Mitógeno
Descriptor French: Mitogen-Activated Protein Kinases
Entry term(s): Kinase, Mitogen-Activated Protein
Kinases, Mitogen-Activated Protein
Mitogen Activated Protein Kinase
Mitogen Activated Protein Kinases
Mitogen-Activated Protein Kinase
Protein Kinase, Mitogen-Activated
Protein Kinases, Mitogen-Activated
Tree number(s): D08.811.913.696.620.682.700.567
D12.644.360.450
D12.776.476.450
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D020928
Scope note: A superfamily of PROTEIN-SERINE-THREONINE KINASES that are activated by diverse stimuli via protein kinase cascades. They are the final components of the cascades, activated by phosphorylation by MITOGEN-ACTIVATED PROTEIN KINASE KINASES, which in turn are activated by mitogen-activated protein kinase kinase kinases (MAP KINASE KINASE KINASES).
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.7.11.24
Previous Indexing: Ca(2+)-Calmodulin Dependent Protein Kinase (1994-1999)
Protein Kinases (1989-1999)
Protein-Serine-Threonine Kinases (1993-1999)
Protein-Tyrosine Kinase (1989-1999)
Public MeSH Note: 2000; for EXTRACELLULAR SIGNAL-REGULATED KINASES see CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE 1994-1999
History Note: 2000; for EXTRACELLULAR SIGNAL-REGULATED KINASES use CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE 1994-1999
Related: MAP Kinase Signaling System MeSH
DeCS ID: 34450
Unique ID: D020928
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2000/01/01
Date of Entry: 1999/11/03
Revision Date: 2020/05/27
Mitogen-Activated Protein Kinases - Preferred
Concept UI M0328039
Scope note A superfamily of PROTEIN-SERINE-THREONINE KINASES that are activated by diverse stimuli via protein kinase cascades. They are the final components of the cascades, activated by phosphorylation by MITOGEN-ACTIVATED PROTEIN KINASE KINASES, which in turn are activated by mitogen-activated protein kinase kinase kinases (MAP KINASE KINASE KINASES).
Preferred term Mitogen-Activated Protein Kinases
Entry term(s) Kinase, Mitogen-Activated Protein
Kinases, Mitogen-Activated Protein
Mitogen Activated Protein Kinase
Mitogen Activated Protein Kinases
Mitogen-Activated Protein Kinase
Protein Kinase, Mitogen-Activated
Protein Kinases, Mitogen-Activated



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