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Descriptor English: Cyclotides
Descriptor Spanish: Ciclotidas
Descriptor ciclótidos
Entry term(s) ciclotida
Scope note: Círculo continuo de enlaces peptídicos, compuesto típicamente de 2-3 docenas de AMINOÁCIDOS, con lo que no existen extremos carboxilicos o amínicos libres. Se caracterizan además por seis residuos conservados de CISTEÍNA que forman MOTIVOS NUDO DE CISTINAS.
Descriptor Portuguese: Ciclotídeos
Descriptor French: Cyclotides
Entry term(s): Cyclotide
Tree number(s): D12.644.641.243
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D047169
Scope note: A continuous circle of peptide bonds, typically of 2-3 dozen AMINO ACIDS, so there is no free N- or C-terminus. They are further characterized by six conserved CYSTEINE residues that form CYSTINE KNOT MOTIFS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Previous Indexing: Peptides, Cyclic (2000-2004)
Public MeSH Note: 2005
History Note: 2005
DeCS ID: 38752
Unique ID: D047169
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2005/01/01
Date of Entry: 2004/07/07
Revision Date: 2020/05/27
Cyclotides - Preferred
Concept UI M0456600
Scope note A continuous circle of peptide bonds, typically of 2-3 dozen AMINO ACIDS, so there is no free N- or C-terminus. They are further characterized by six conserved CYSTEINE residues that form CYSTINE KNOT MOTIFS.
Preferred term Cyclotides
Entry term(s) Cyclotide



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